Hydrogentest breathing with different quantity of lactose in detecting lactase deficiency disease
Huang Huide
Author information+
(Huang HD)，Wang Mingchun(Wang MC)，Huang Liuye(Huang LY)，et al
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History+
Received
Published
1997-12-17
1998-05-05
Issue Date
1998-05-05
Abstract
OBJECTIVE: To find out the tolerance to lactose of Chinese. METHODS: Hydrogen breathing test (HBT) was used in 136 healthy adults of the Han nationality with different quantity of lactose A, B, C. The different groups of subjects were given 25 g, 12.5 g, 6.25 g lactose respectively. The subjects of the C group taking lactose with HBT negative were given 12.5 g lactose again were included the in D group. RESULTS: The test showed that the incidence of malabsorption for lactose of the A, B, C, D groups was respectively 85.0%, 48.9%, 2% and 46.7%. The intolerance was 54.3%, 30.4%, 2.0% and 20.0% respectively. The incidence of malabsorption of and intolerance to lactose were significently different among the A, B and C groups (P<0.001). There was no significant difference between the B and D groups (P>0.05). CONCLUSION: The tolerance quantity of lactose for Chinese is 6.25 g. Taking 125 ml milk for each time is reasonable.
Hung Huide.
Hydrogentest breathing with different quantity of lactose in detecting lactase deficiency disease [J]. Chinese Pharmaceutical Journal, 1998, 33(05): 308-310
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References
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