Stability and dissolution study of propiverine hydrochloride tablets

Liu Yuling

Chinese Pharmaceutical Journal ›› 1997, Vol. 32 ›› Issue (04) : 229-231.

Chinese Pharmaceutical Journal ›› 1997, Vol. 32 ›› Issue (04) : 229-231.
药品检验

Stability and dissolution study of propiverine hydrochloride tablets

  • Liu Yuling
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Abstract

OBJECTIVE:To investigate the stability and dissolution of propiverine hydrochloride tablets systematically.METHODS: HPLGUV was used to determine the stability and dissolution of the samples to be laid in the condition of severe test, accelerated test and long-term storage test. RESULTS:Outward appearance, content, related substance and dissolution of the samples were not changed, and the dissolution rate was more than 85% in 45 min. CONCLUSION:The results show that propiverine hydrochloride tablets have good stability and dissolution.

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propiverine hydrochloride / HPLC / stability / dissolution

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Liu Yuling. Stability and dissolution study of propiverine hydrochloride tablets[J]. Chinese Pharmaceutical Journal, 1997, 32(04): 229-231

References

1 横山修,宫崎公臣,石田武之,等.频尿,尿失禁症例に对する盐酸プロピベリンの使用经验.泌尿纪要,1980,36:517. 2 大友英一,丸山腾一,小林逸郎,等.神经疾患に伴ろ排尿障害に对する盐酸プロピベリン(p-4)の临床评价.药理と治疗,1990,18(4):367. 3 中国药典1995年版.二部.1995:附录66.

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