Fermentation and extraction of Leiwan( Omphalia lapidescens Schroet)proteinase and its activation againt cysticercus cellulosae in vitro

Guo Modi

Chinese Pharmaceutical Journal ›› 1997, Vol. 32 ›› Issue (02) : 75-77.

Chinese Pharmaceutical Journal ›› 1997, Vol. 32 ›› Issue (02) : 75-77.
中药及天然药物

Fermentation and extraction of Leiwan( Omphalia lapidescens Schroet)proteinase and its activation againt cysticercus cellulosae in vitro

  • Guo Maodi
Author information +
History +

Abstract

OBJECTIVE: To investigate whether the fermentation products of Omphalia lapidescens Schroet strain contain Leiwan proteinase with molecular weight and parasiticide effect on cysticercus cellulosae in vitro both similar to these of natural Leiwan. METHODS: We examined the fermentation products of Omphalia lapidescens Schroet strain, and tested the parasiticide effect on cysticercus cellulosae in vitro, in comparison with the natural Leiwan proteinase RESULTS: In the Leiwan proteinase extracted from the fermentation products of Omphalia Lapidescens Schroet strain, the molecular weight was 16 800, PI 4.4,and amino terminal valine. It had proteolysis activity and parasiticide effect on cysticercus cellulosae in vitro .CONCLUSION: There were no remarkable differences between the Leiwan proteinase obtained by the method of Omphalia Lapidescens Schroet strain fermenting, and the natural Leiwan proteinase.

Key words

Omphalia lapidescens Schroet / proteinase / cysticercus cellulosae

Cite this article

Download Citations
Guo Modi. Fermentation and extraction of Leiwan( Omphalia lapidescens Schroet)proteinase and its activation againt cysticercus cellulosae in vitro[J]. Chinese Pharmaceutical Journal, 1997, 32(02): 75-77

References

1 刘波.中国药用真菌.第2版.太原:山西人民出版社,1978. 2 景厚德.雷丸驱绦虫的介绍,中华新医学报,1951,10:753. 3 董泉洲,李明.雷丸蛋白酶提纯及其化学成分的研究.中成药,1991,3:32. 4 杜传馨,李明.雷丸蛋白酶性质研究.中草药,1987,3:18. 5 北京大学生物系生物化学教研室.生物化学实验指导.北 京:高等教育出版社,1979. 6 中山大学生物系生化微生物教研室.生化技术导论.北京: 人民教育出版社,1979.

54

Accesses

0

Citation

Detail

Sections
Recommended

/