Construction Study of Index System to Evaluate the Clinical Value of Drugs

ZHANG Fang,ZHANG Da-wei,MENG Li-hua,DAI Gang,GUAN Yi-ru,LU Bi-xiang,LI Tong-tong,WU Zhi-ang*

Chinese Pharmaceutical Journal ›› 2017, Vol. 52 ›› Issue (8) : 706-711.

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Chinese Pharmaceutical Journal ›› 2017, Vol. 52 ›› Issue (8) : 706-711. DOI: 10.11669/cpj.2017.08.021

Construction Study of Index System to Evaluate the Clinical Value of Drugs

  • ZHANG Fang1, ZHANG Da-wei1, MENG Li-hua2, DAI Gang1,3, GUAN Yi-ru1, LU Bi-xiang1, LI Tong-tong1, WU Zhi-ang1*
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Abstract

OBJECTIVE To analyze the connotation and composition of the clinical value of drugs, and to build the index system for the evaluation of drug's clinical value, hence to provide references for its scientific evaluation. METHODS We designed the preliminary constructs index system referencingmedicine clinical evaluation indicatorsof German and French firstly. And then the expert interview and Delphi survey were used to analysis to determine the index system and index weight of medicine clinical evaluation. RESULTS The classified index system of the clinical value was established, which was composed of 2 first-grade indexes including clinical value and innovation value and 15 grade two indexes. Experts were invited to assess the value ranking according to the background information of rosuvastatin, atorvastatin and simvastatin statin drugs by their generic names. The expert's scoring results were summarized to determine the sequence. And it were compared with the average market prices in Germany, France, Britain, the United States, South Korea, Japan and analyzed. CONCLUSION The clinical value of drugs is an international standard for determining the reasonable price of drugs. This research method is feasible to determine the drug prices sequencing by the classified clinical value of drugs in the same kind of product. The price sequencing of some generic names of statin drugs did not correspond with its clinical value sequence, and the price can not reflect its value. The integrity and authenticity of the background data directly determine the classification of the clinical value. Various parties are needed to participate in providing detailed data and information.

Key words

drug's clinical value / index system / Delphi method / statin drugs / drug pricing

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ZHANG Fang,ZHANG Da-wei,MENG Li-hua,DAI Gang,GUAN Yi-ru,LU Bi-xiang,LI Tong-tong,WU Zhi-ang*. Construction Study of Index System to Evaluate the Clinical Value of Drugs[J]. Chinese Pharmaceutical Journal, 2017, 52(8): 706-711 https://doi.org/10.11669/cpj.2017.08.021

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