纳米金的药用研究进展

陆晨熠 庄贞静 邱飞

中国药学杂志 ›› 2012, Vol. 47 ›› Issue (7) : 481-485.

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中国药学杂志 ›› 2012, Vol. 47 ›› Issue (7) : 481-485.
综述

纳米金的药用研究进展

  • 陆晨熠1,2,庄贞静1,2,邱飞1,2*
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Research Progress on Medicinal Application of Gold Nanoparticles

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文章历史 +

摘要

目的 综述近年来纳米金的药用研究进展,为开发纳米金及其相关药物用于疾病治疗提供参考。方法 依据近十年来国内外的文献,就纳米金的药用情况、研究进展和纳米金的毒性等进行归纳、总结。结果与结论 纳米金自身具有生物活性,同时还具有光热效应,也可以作为药物载体使用,3种方式均已用于疾病治疗的研究中。纳米金在艾滋病、肿瘤、帕金森病等疾病治疗研究中已经得到了初步应用,其中抗肿瘤药AurimuneTM (CYT-6091)已经完成Ⅰ期临床试验,正在进行Ⅱ期临床试验。纳米金的药用研究的发展迅速,显示出良好的应用前景。同时,相关研究表明纳米金具有良好的生物相容性,毒性低,但作为药物方面的应用还有待进一步的评价。

关键词

纳米金 / 药用 / 光热效应 / 药物载体 / 靶向给药 / 毒性 / 艾滋病 / 抗肿瘤药 / 帕金森病

引用本文

导出引用
陆晨熠 庄贞静 邱飞. 纳米金的药用研究进展[J]. 中国药学杂志, 2012, 47(7): 481-485
Research Progress on Medicinal Application of Gold Nanoparticles[J]. Chinese Pharmaceutical Journal, 2012, 47(7): 481-485

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基金

国家自然科学基金资助项目 (30900351);福建省自然科学基金资助项目(2009J05029,2010J05026);福建省生物医药工程研究生教育创新基地资助项目 (06070205);华侨大学科研基金资助项目(08BS412)

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