摘要
目的介绍细胞水平的高通量筛选技术研究进展。方法根据近年来文献,综述细胞水平的高通量技术发展趋势和使用技术进展。结果细胞水平筛选是在活细胞自然条件下,接近体内的生化过程,且可以做到多靶点、多指标检测,满足在药物发现早期对药物的综合评价,缩短药物发现周期。结论细胞水平的高通量筛选技术具有广阔前景。
关键词
细胞模型 /
高通量药物筛选 /
药物发现
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李韶菁;杜冠华.
细胞水平的高通量药物筛选技术研究进展[J]. 中国药学杂志, 2008, 43(02): 84-87
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脚注
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基金
国家863重点专项基金项目(2004AA2Z3782);国际科技合作项目(2006DFA31420);国家自然基金资助项目(0630073)
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