Abstract：The widespread use of antibiotics has solved many infection problems, but it has also led to the emergence of more and more resistant bacteria. The killing effect of traditional antibiotics on resistant bacteria has been weakened, which increaseits threat constantly. Therefore, in order to combat the growing resistance of bacteria, it is urgent to develop new antibacterial substances and find new antibacterial mechanisms. With its unique properties, nano-metal materials have slowly shown their potential as broad-spectrum antibacterial agents. Among them, the effect of zinc oxide nanoparticles(ZnO-NPs) is better, which can kill bacteria through mechanisms such as generation of active oxygen, dissolution of zinc ions, and direct contact. Based on this antibacterial property ZnO-NPs has also been applied in some fields, such as medical, food packaging, textiles, which has great potential. The disscussion of the antibacterial mechanism and antibacterial application of ZnO-NPs will be a focus.
张钧凯, 金学睿, 严吉, 陈璨羽, 邓国英. 纳米氧化锌抑菌机制与应用进展[J]. 中国药学杂志, 2022, 57(24): 2045-2050.
ZHANG Jun-kai, JIN Xue-rui, YAN Ji, CHEN Can-yu, DENG Guo-ying. Antibacterial Mechanism and Application Progress of Zinc Oxide Nanoparticles. Chinese Pharmaceutical Journal, 2022, 57(24): 2045-2050.
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