Abstract：OBJECTIVE To analyze the quality value transmitting relationship of ligustilide between medical herbs-decoction pieces-whole decoction of Angelicae Sinensis Radix (ASR) based on traditional decoction process. METHODS The content and the transfer rate of ligustilide were used as indicators to analyze the quality value transmitting relationship between medical herbs-decoction pieces-whole decoction of ASR. RESULTS The content ranges of ligustilide in medical herbs, decoction pieces and whole decoction were 0.958 5%-1.572 7%, 0.608 9%-0.815 6% and 0.035 6%-0.055 9%. The transfer rate of ligustilide from medical herbs to decoction pieces was between 51.84% and 66.07%, the average transfer rate was 60.82%; the transfer rate of ligustilide from decoction pieces to whole decoction was between 4.94% and 8.78%, the average transfer rate was 6.46%. CONCLUSION Traditional Chinese medicine compounds based on traditional decoction process remain volatile components, and METHODS were simple, accurate, stable and sensitive,and can provide a reference for the transformation and development of modern preparations which contain volatile components.
庄欣雅, 亓雅丽, 张倩, 潘金火, 毛春芹, 陈军, 严国俊. 基于传统水煎煮工艺的当归中挥发性成分藁本内酯的量值传递研究[J]. 中国药学杂志, 2022, 57(8): 628-635.
ZHUANG Xin-ya, QI Ya-li, ZHANG Qian, PAN Jin-huo, MAO Chun-qin, CHEN Jun, YAN Guo-jun. Quality Value Transmitting of Volatile Components Ligustilide of Angelicae Sinensis Radix Based on Traditional Decoction Process. Chinese Pharmaceutical Journal, 2022, 57(8): 628-635.
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2022, Vol. 57 
