Abstract：OBJECTIVE To enrich the chemical constituents of Ardisia crispa(Thunb.) A. DC.. METHODS The 70% ethanol extract of Ardisia crispa (Thunb.) A. DC. was isolated and purified by silica, recrystallization, ODS and preparative / semi-preparative HPLC, and the structures of obtained compounds were identified by physico-chemical properties and spectroscopic data. RESULTS The compounds are bergenin (1), methylbergenin (2), 11-O-galloylbergenin (3), syringin (4), (+)-syringaresinol-O-β-D-glucopyranoside (5), (-)-(7R, 8S, 7′R, 8′S)-4, 9, 4′, 9′-tetrahydroxy-3, 3′-dimethoxy-7, 7′-epoxylignan-9-O-β-D-xylopyranoside (6), saracoside (7), isolariciresinol-4-O-β-D-glucopyranoside (8), (7S, 8R)-urolignoside (9), staphylionoside D (10), grasshopper ketone (11), l-borneol 6-O-β-D-aiosyl-β-D-glucoside (12), (+)-angelicoidenol-2-O-β-D-glucopyranoside (13), vitexin-2″-O-rhamnoside (14), phlorizin (15), phenethyl alcohol-β-D-(2′-O-β-D-glucopyranosyl) glucopyranoside (16), phenylethyl-β-D-glucopyranoside (17), tatarine C (18), caprolactam (19) and sucrose (20). CONCULUSION Compounds 5-19 are firstly isolated from the family Myrsinaceae, compound 4 is isolated from genus Ardisia for the first time and compound 2 and 3 are obtained from this plant for the first time. Compound 6 is the second occurrence ever domestic scholars obtained it from Rhododendron mariae Hance in 2013.
胡瑞航, 殷鑫, 周永强, 雷传文, 朱蔚芊, 周英. 百两金根的化学成分研究[J]. 中国药学杂志, 2022, 57(8): 605-612.
HU Rui-hang, YIN Xin, ZHOU Yong-qiang, LEI Chuan-wen, ZHU Wei-qian, ZHOU Ying. Chemical Constituents from the Roots of Ardisia crispa (Thunb.) A. DC.. Chinese Pharmaceutical Journal, 2022, 57(8): 605-612.
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