Reaserch Progress on Anticancer effect of Cordycepin and its Mechanism
ZHANG An-yong1, XIONG Qiu-ping2, LIU Xin-ping1,3, YAO Li-hua1,3*
1. College of Life Sciences, Jiangxi Science and Technology Normal University, Nanchang 330013, China; 2. Department of Digestive Oncology, Affiliated Cancer Hospital of Nanchang University, Nanchang 330029, China; 3. Jiangxi Fungi Grass Biotechnology Co., Ltd., Nanchang 330013, China
Abstract：With the increasing incidence and mortality of cancer, people have paid more and more attention to the research of anticancer drugs. Cordycepin has been a research hotspot in the field of medicinal chemistry because of its broad-spectrum biological activities such as antibacterial, antiviral, antitumor, antioxidant, anti-aging and immunomodulation, and pioneering achievements have been made in application research. In order to provide reference for cancer treatment with cordycepin, this paper reviewed the anticancer research of cordycepin and its mechanism. Meanwhile the effects of cordycepin on apoptosis, cell cycle arrest, cancer cell metastasis inhibition, tumor suppressor gene expression regulation and adjuvant participation in combination therapy are elaborated.
张安勇, 熊秋萍, 刘新平, 姚丽华. 虫草素的抗癌作用及其机制研究进展[J]. 中国药学杂志, 2021, 56(20): 1664-1670.
ZHANG An-yong, XIONG Qiu-ping, LIU Xin-ping, YAO Li-hua. Reaserch Progress on Anticancer effect of Cordycepin and its Mechanism. Chinese Pharmaceutical Journal, 2021, 56(20): 1664-1670.
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2021, Vol. 56 
