Phenolic Constituents from the Fruit of Chaenomeles sinensis
SHI Jing-ya1,2, ZHANG Zhi-guang1,2, LI Meng1,2, ZHANG Jing-ke1,2, LÜ Jin-jin1,2, ZHENG Xiao-ke1,2, FENG Wei-sheng1,2*
1. Henan University of Chinese Medicine, Zhengzhou 450046, China; 2. Collaborative Innovation Center for Respiratory Disease Diagnosis and Treatment & Chinese Medicine Development of Henan Province, Zhengzhou 450046, China
Abstract：OBJECTIVE To investigate the chemical constituents from the fruit of Chaenomeles sinensis(Thouin) Koehne and identify their structures. METHODS The 50% acetone extract of C. sinensis was isolated and purified by macroporous adsorption resin, Toyopearl HW-40, YMC-Pack ODS and Sephadex LH-20 column chromatography. And the molecular structures of the obtained compounds were identified by physicochemical properties and spectral data. RESULTS Twenty phenolic compounds were isolated and their structures were identified as 6-O-(E)-feruloyl-β(α)-glucopyranoside(1), 2, 4, 6-trihydroxy acetophenone-2-O-glucopyranoside(2), (E)-4-hydroxycinnamyl alcohol 4-O-β-D-glucopyranoside(3), 3, 4, 5-trimethoxyphenyl-1-O-β-D-glucopyranoside(4), cis-coniferin(5), syringing(6), 4-(2, 3-dihydroxypropyl)-2, 6-dimethoxyphenyl-β-D-glucopyranoside(7), (7S, 8S)-syringoylglycerol-9-O-β-dglucopyranoside(8), L-threo-guaiacylglycerol-8-O-β-glucopyranoside(9), 3, 5-dimethoxy-4-O-β-D-glucopyranosylphenylpropane-7, 9-diol(10), 3-methoxy-4-hydroxyphenol 1-O-β-apiofuranosyl-(1→6)-O-β-D-glucopyranoside(11), 3, 4, 5-trimethoxyphenol 1-O-β-D- apiofuranosyl-(1→6)-β-D-glucopyranoside(12), dihydrosyringin(13), divarin-3-O-β-glucopyranoside(14), ω-hydroxypropioguaiacone(15), dihydrosyringenin(16), 3, 4-dihydroxybenzoic acid(17), vanillic acid(18), 1, 3, 5-trimethoxybenzene(19), and p-hydroxyphenylpropionic acid(20). CONCLUSION Compounds 1-20 are isolated from this plant for the first time.
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2020, Vol. 55 
