Cytokine Storm Induced by SARS-CoV-2 and the Drug Therapy
ZHANG Jing-wen1,2, HU Xin2, JIN Peng-fei2*
1. Department of Pharmacy Administration and Clinical Pharmacy,School of Pharmaceutical Science, Peking University, Beijing 100191, China; 2. Department of Pharmaceutical Science, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Science, Beijing Key Laboratory of Drug Clinical Risk and Personalized Medication Evaluation, Beijing 100730, China
Abstract:Novel coronavirus 2019 (SARS-CoV-2) infection outbreak has occurred in Wuhan since December 2019.Cytokine storm (inflammatory factor storm)was suggested to be involved in the sudden deterioration of some SARS-CoV-2 infectors in the recent reports.However, no medicine was specific to the treatment of cytokine storm so far. This paper summarized the mechanism and potential therapeutic drugs of cytokine storm based on literature review and analysis, so as to provide references for the treatment of SARS-CoV-2.
张竞文, 胡欣, 金鹏飞. 新型冠状病毒引起的细胞因子风暴及其药物治疗[J]. 中国药学杂志, 2020, 55(5): 333-336.
ZHANG Jing-wen, HU Xin, JIN Peng-fei. Cytokine Storm Induced by SARS-CoV-2 and the Drug Therapy. Chinese Pharmaceutical Journal, 2020, 55(5): 333-336.
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