Quality Evaluation of Fritillariae Cirrhosae Bulbus Based on Traditional Character Analysis
LI Rui-qi1,2,3,4, WU Cui2,3, XU Liang2,3, MA Yu-cui2,3, CHEN Yuan1, CHAO Zhi-mao2,3*
1. Agronomy College, Gansu Agricultural University, Lanzhou 730070, China; 2. Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China; 3. Storage & Packaging Position, Chinese Materia Medica, China Agriculture Research System, Beijing 100700, China; 4. Dingxi Institute for Drug Control, Dingxi 743000, China
Abstract：OBJECTIVE To improve the quality evaluation method of Fritillariae Cirrhosae Bulbus by the means of objective quantization of appearance character. METHODS The height and diameter were measured by a vernier caliper. The color of powder was determined by a colorimeter based on the human eye observation. The content of total alkaloids was measured by the ultraviolet spectroscopy. Some correlation analysis between the content of total alkaloids and height, diameter, and △E value were evaluated by a SPSS software, respectively. RESULTS There were a very significant negative correlation (P＜0.01) between height and the total alkaloids, a negative correlation between diameter and the total alkaloids, and no significant correlation between △E value and the total alkaloids. CONCLUSION Because the content of total alkaloids could reflect the quality of Fritillariae Cirrhosae Bulbus objectively, these RESULTS of this study provide a scientific basis for the traditional ideas of “the smaller the best” and “the broken Fritillariae Cirrhosae Bulbus could not be used as medicine” and affirm the traditional processing technology that “should not be washed by water”. Songbei was the best Fritillariae Cirrhosae Bulbus of them all.
李瑞琦, 吴翠, 徐靓, 马玉翠, 陈垣, 巢志茂. 基于传统性状客观化分析的川贝母质量评价[J]. 中国药学杂志, 2020, 55(1): 14-18.
LI Rui-qi, WU Cui, XU Liang, MA Yu-cui, CHEN Yuan, CHAO Zhi-mao. Quality Evaluation of Fritillariae Cirrhosae Bulbus Based on Traditional Character Analysis. Chinese Pharmaceutical Journal, 2020, 55(1): 14-18.
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2020, Vol. 55 
