Abstract：OBJECTIVE To establish the detection method of Liriopes Radix in Niuhuang Qingwei pills to uncover the adulteration situation of Ophiopogonis Radix in Niuhuang Qingwei pills. METHODS Liriopesides B and liriope muscari baily saponins C in Niuhuang Qingwei pills were analyzed by HPLC-MS-MS in MRM mode. RESULTS In the 18 batches of Niuhuang Qingwei pills, liriopesides B and liriope muscari baily saponins C, the index compounds of Liriopes Radix, were detected in 15 batches of samples in the concentrations of 0.10-1.19 μg·g-1. CONCLUSION The adulteration of Ophiopogonis Radix with Liriopes Radix should be paid more attention to.
王峰, 何轶, 于健东, 戴忠, 马双成. 牛黄清胃丸中麦冬掺伪情况研究[J]. 中国药学杂志, 2019, 54(16): 1332-1335.
WANG Feng, HE Yi, YU Jian-dong, DAI Zhong, MA Shuang-cheng. Adulteration Situation of Ophiopogonis Radix in Niuhuang Qingwei Pills. Chinese Pharmaceutical Journal, 2019, 54(16): 1332-1335.
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