Chemical Constituents from Laportea bulbifera, a Zhuang Medicine
WANG Yu-meng1, WEN Hai-cheng2, DOU De-qiang1*
1. School of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian 116600, China; 2. Guangxi University of Chinese Medicine, Nanning 530001, China
Abstract��OBJECTIVE To study the chemical constituents from Laportea bulbifera. METHODS The 60% ethanol extract from L. bulbifera was isolated and purified by chromatography on silica, Sephadex LH-20, and ODS, recrystallization, and semi-preparative HPLC. Their chemical structures were elucidated by physicochemical properties and spectroscopic methods. RESULTS These compounds were determined as ��-sitosterol(1), protocatechuic acid ethyl ester(2), scopoletin (3), trans-cinnamic acid (4),trans-p-hydroxycinnamic acid(5), kaempferol 7-O-rhamnoside(6), luteolin(7), ethyl gallate(8), (+)-isolarisiresinol 3a-O-��-D-glucopyranoside(9), and kaempferitrin(10). CONCLUSION Compounds 2, 5, 7-9 are isolated from genus Laportea for the first time, and compounds 2-5,7-9 are isolated from this plant for the first time.
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2019, Vol. 54 
