Advances in Evaluation Methods and Models on Angiogenesis
CUI He-rong1, LI Hong-yan2, JIANG Wen-yan3, MA Tao1, WANG Peng-long1*, LEI Hai-min1*
1. School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China; 2. School of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian 116600, China; 3. College of Life Science and Biotechnology, Beijing University of Technology, Beijing 100124, China
Abstract��Angiogenesis, the process of shaping new vessels from existing or posteriorvessels. It occurs mainly after birth and is the basis for the formation of many vascular structures and participates ina variety of physiological and pathological processes.Due to the particularity of the research objects and the diversity of the species, the experimental results obtained from one model may not be confirmed on the other model. At present,the comprehensive evaluation of angiogenesis requires mutual verification of different model results. Herein, this review mainly summarizes the literatures on the evaluation of angiogenesis activity within recent ten years. From three parallel dimensions of cell, tissue, and animal,the up-to-date evaluation methods and angiogenesis models with wide recognitions are reviewed, in order to provide the reference for related drug research and development.
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CUI He-rong, LI Hong-yan, JIANG Wen-yan, MA Tao, WANG Peng-long, LEI Hai-min. Advances in Evaluation Methods and Models on Angiogenesis. Chinese Pharmaceutical Journal, 2019, 54(9): 677-681.
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2019, Vol. 54 
