Analysis of Antibacterial Utilization for Patients with Acute Upper Respiratory Tract Infections in Community Health Care Institutions in Dongcheng District of Beijing
FU Meng-yuan1, XIE Jin-xi1, WANG Fang2, ZHAO Dong-ming2, CHEN Zi-hao3,4, SHI Lu-wen1,3, GUAN Xiao-dong1,3*
1. School of Pharmaceutical Sciences, Peking University, Beijing 100191, China; 2. Dongcheng District Community Health Service Management Center, Beijing 100010, China; 3. International Research Center of Medicinal Administration, Peking University, Beijing 100191,China; 4. Office of the President, Peking University Health Science Center, Beijing 100191, China
Abstract��OBJECTIVE To investigate the use of antibacterials for patients with acute upper respiratory tract infections(AURIs) in community health care institutions in Dongcheng district, so as to provide references for rational use of antibacterials in primary health care institutions. METHODS All the outpatient prescriptions of AURIs patients from 65 primary health care institutions in Dongcheng district in 2016 were selected. The antibacterial and multiple antibacterial prescription rate were analyzed from the perspective of drug categories, patients�� and doctors�� characteristics. RESULTS This study included 164 575 AURIs prescriptions of community health care institutions in Dongcheng district in 2016. The antibacterial prescription rate(APR)was 12.1% and the multiple antibacterial prescription rate(MAPR) was 0.6%. The top antibacterials in the list of varieties were second generation cephalosporin(60.2%) and macrolide(16.2%), the penicillin preferred by the guidelines were not used. The APR for the male and patients with acute laryngitis or acute tonsillitis was higher. Compared with patients 18-50 years old,the use and combination of antibacterials for patients >50 years old werehigher(P<0.05).There were significant differences in the use and combination of antibacterials among doctors of different genders, education and titles(P<0.05). CONCLUSION The issue of antibacterial abuse in the AURIs treatment in primary health care institutions should be given sufficient attention. Regular standardized antibacterial treatments training and continuing education for all doctors in primary health care institution are necessary.
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FU Meng-yuan, XIE Jin-xi, WANG Fang, ZHAO Dong-ming, CHEN Zi-hao, SHI Lu-wen, GUAN Xiao-dong. Analysis of Antibacterial Utilization for Patients with Acute Upper Respiratory Tract Infections in Community Health Care Institutions in Dongcheng District of Beijing. Chinese Pharmaceutical Journal, 2018, 53(21): 1881-1884.
PAUL M. Antibiotic prescribing for nonbacterial acute upper respiratory infections in elderly persons[J]. Ann Intern Med, 2017,167(10):757-758.
[2]
WANG Y. Evaluation of implementing antibiotic prescription strategy in the treatment of acute upper respiratory tract infection[J]. J Clin Med Liter(�ٴ�ҽҩ��������־), 2017,4(38):7485.
[3]
LIU Y, LIU M, HAN C C,et al. Investigation of categories of common diseases and medicines used among patients in community health service institutions in Beijing[J]. Chin Gen Prac(�й�ȫ��ҽѧ), 2009,12(11):1024-1027.
[4]
National Health and Family Planning Commission of the People��s Republic of China. Guidelines for Clinical Use of Antibacterials(2015)(����ҩ���ٴ�Ӧ��ָ��ԭ��(2015)) [EB/OL]. [2017-12-24]. http://www. nhfpc. gov. cn/yzygj/s3593/201508/c18e1014de6c45ed9f6f9d592b43db42. shtml
[5]
ARROLL B. Antibiotics for upper respiratory tract infections: an overview of cochrane reviews[J]. Respir Med, 2005,99(3):255-261.
[6]
DEL MAR C, GLASZIOU P, LOWE J B, et al. Addressing antibiotic resistance��focusing on acute respiratory infections in primary care[J]. Aust Fam Phys, 2012,41(11):839-840.
[7]
LI W M, LU Y L, CHEN M Y, et al. Meta-analysis on antibiotics usage in children with upper respiratory tract infection in China[J]. Chin Pharm J(�й�ҩѧ��־), 2017, 52(10):880-885.
[8]
LI J, SONG X, YANG T, et al. A systematic review of antibiotic prescription associated with upper respiratory tract infections in China[J]. Med(Baltimore), 2016,95(19):e3587.
[9]
GE J B, XU Y J. Internal Medicine(�ڿ�ѧ)[M]. 8th ed. Beijing: People��s Medical Publishing House,2013:13-16.
[10]
BAKARE T M, SCHATTNER P. The usefulness of a clinical ��scorecard�� in managing patients with sore throat in general practice[J]. Asia Pac Fam Med, 2010,9(1):9.
[11]
WONG M C, CHUNG C H. Group A streptococcal infection in patients presenting with sore throat at an accident and emergency department: prospective observational study[J]. Hong Kong Med J, 2002,8(2):92-98.
[12]
CHEN X Q, JIN Y G, TANG G. New Materia Medica(�±�ҩ��ѧ) [M].Vol 17. Beijing:People��s Medical Publishing House, 2014:63-64.
[13]
CAI W Q, ZHOU Z J. Antibiotics use in tertiary general hospitals outpatient clinic, Beijing[J]. Mod Prevent Med(�ִ�Ԥ��ҽѧ), 2017,44(5):954-960.
[14]
National Health and Family Planning Commission of the People��s Republic of China.The Administration on the Clinical Use of Antimicrobial Agents and the Status Quo of Antimicrobials Resistance in China(2017)[�й�����ҩ������ϸ����ҩ��״����(2017��)] [M]. Beijing:Peking Union Medical College Press,2017:4.
[15]
WU Y Q, XI H X, ZHANG Y, et al. Utilization of antibacterial agents for emergency patients with acute upper respiratory infections in tertiary hospitals in Beijing[J]. J Peking Univ(Health Sciences)(������ѧѧ��:ҽѧ��), 2014,46(3):435-439.
[16]
MUSTAFA M, WOOD F, BUTLER C C, et al. Managing expectations of antibiotics for upper respiratory tract infections: a qualitative study[J]. Ann Fam Med, 2014,12(1):29-36.
[17]
GAARELEV C, YEE M, CHAN G, et al. A mixed methods study to understand patient expectations for antibiotics for an upper respiratory tract infection[J]. Antimicrob Resist In, 2016,5(1):39.
[18]
ROUSOUNIDIS A, PAPAEVANGELOU V, HADJIPANAYIS A, et al. Descriptive study on parents�� knowledge, attitudes and practices on antibiotic use and misuse in children with upper respiratory tract infections in cyprus[J]. Int J Environ Res Public Health, 2011,8(8):3246-3262.
[19]
SUN Q, DYAR O J, ZHAO L, et al. Overuse of antibiotics for the common cold-attitudes and behaviors among doctors in rural areas of Shandong province, China [J]. BMC Pharmacol Toxicol, 2015,16(1):6.
[20]
SHENG F, CHE L, LIU P Y, et al. Behavior making doctors prescribe antibiotics in acute upper respiratory tract infections[J]. Basic Clin Med(����ҽѧ���ٴ�), 2014,34(4):570-572.
2018, Vol. 53 
