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Application of Drosophila melanogaster in Pharmacological Research
DUAN Dan-dan1a,1b, GAO Li1a*, QIN Xue-mei1a*, ZHOU Yu-zhi1a, DU Guan-hua2
1a. Modern Research Center for Traditional Chinese Medicine; 1b. College of Chemistry and Chemical Engineering, Shanxi University, Taiyuan 030006, China; 2. Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
Abstract��As a model organism, Drosophila melanogaster has the characteristics of short life cycle, high fecundity and high gene conservation. At present, Drosophila melanogaster has been widely used in the studies of pharmacology and pathogenesis, including aging, neurodegenerative disease, insomnia, tumor and other fields, which show potential values in accelerating the speed of drug screening and target discovery. In this paper, the advantages of Drosophila as a model organism, the applications and limitations of Drosophila in pharmacological studies were reviewed.
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2016, Vol. 51 
