目的 研究辛夷(Magnolia biondii Pamp.)的化学成分。方法 利用Diaion HP-20,Toyopearl HW-40,硅胶柱及半制备液相等多种色谱技术进行分离纯化,根据化合物的理化性质和光谱数据鉴定结构。结果 分离并鉴定了14个化合物的结构,分别为香草酸-4-O-β-D-葡萄糖苷(1),3-甲氧基-4-羟基苯-1-O-β-D-葡萄糖苷(2),香草酸甲酯(3),咖啡酸(4),3, 4, 5-三甲氧基苯-1-O-β-D-葡萄糖苷(5),苄基-O-β-D-葡萄糖苷(6),苄基-O-β-D-半乳糖苷(7),紫丁香苷(8),香草酸葡萄糖酯(9),香草酸(10),1′-(3, 4-二羟基肉桂酰)环戊烷-2′, 3′-二醇(11),东莨菪苷(12),7-甲氧基香豆素-6-O-β-D-葡萄糖苷(13)和莨菪亭(14)。结论 化合物1~9,11~13为首次从该植物中分离得到。
Abstract
OBJECTIVE To study the chemical constituents of Magnolia biondii.Pamp. METHODS The compounds were isolated and purified by Diaion HP-20, Toyopearl HW-40, silica gel column chromatography and semi-preparative HPLC and so on. The structures were elucidated on the basis of spectral data and physiochemical properties. RESULTS Fourteen compounds were isolated and identified as 4-O-β-D-glucopyranosylvanillic acid(1), tachinoside(2), methyl 4-hydroxy-3-methoxybenzoate(3), caffeic acid(4), 3,4,5-trimethoxyphenyl-β-D-glucopyranoside(5), benzyl-O-β-D-glucopyranoside(6), benzyl-O-β-D-galactopyranoside(7), syringin(8), vanillic acid glucosyl ester(9), vanillic acid(10), 1′-(3,4-dihydroxycinnamoyl)cyclopentane-2′,3′-diol(11), scopolin(12),7-methoxycoumarin-6-O-β-D-glucopyranoside(13), and scopoletin(14). CONCLUSION Compounds 1-9 and 11-13 are isolated from this plant for the first time.
关键词
木兰科 /
辛夷 /
酚酸 /
香豆素 /
紫丁香苷 /
咖啡酸
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Key words
Magnoliaceae /
Magnolia biondii Pamp. /
phenolic acid /
coumarin /
syringin /
caffeic acid
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中图分类号：
R284
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参考文献
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脚注
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基金
教育部科学技术研究重点资助项目(DF2003078)
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