Abstract��OBJECTIVE To establish a quantitative analysis of multi-components by single-marker (QAMS) method for determination of uridine, guanosine and adenosine in Cordyceps sinensis. METHODS Adenosine was used as the marker to calculate the relative correction factors (RCF) for uridine and guanosine by using high performance liquid chromatography(HPLC). Both QAMS method and external standard method (ESM) were performed to determine the three kinds of nucleosides in Cordyceps sinensis. RESULTS There were no significant differences between the two methods. CONCLUSION The developed QAMS method is feasible to evaluate the quality of Cordyceps sinensis.
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QIAN Zheng-ming, SUN Min-tian, AI Zhong, LIAO Na, ZHOU Miao-xia, LI Wen-jia, LI Wen-qing. Simultaneous Determination of Three Nucleosides in Cordyceps sinensis by QAMS. Chinese Pharmaceutical Journal, 2015, 50(15): 1297-1300.
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2015, Vol. 50 
