目的 探讨何首乌中无机元素的动态变化。方法 采用电感耦合等离子体质谱法(ICP-MS)测定不同采收时间何首乌无机元素含量,用SPSS16.0对数据进行相关性分析。结果 共检测了23种元素,且元素相互之间有一定的相关性,部分元素动态积累呈现一定规律性。结论 何首乌中重金属积累曲线最小峰值所对应的时间与传统采收期基本一致,为确定何首乌的适宜采收期提供依据。
Abstract
OBJECTIVE To explore the dynamic changes of the inorganic elements in Polygoni Multiflori Radix. METHODS The sample solutions were analyzed by ICP-MS after microwave digestion and the contents of elements were calculated according to their calibration curves. Correlation analysis was performed with the SPSS16.0 software. RESULTS Twenty-three inorganic elements were detected in Polygoni Multiflori Radix, and there were some correlations among the contents of these inorganic elements. Certain rules existed in the dynamic accumulation of the some elements. CONCLUSION The minimum peak of the accumulation curve for the heavy metal in Polygoni Multiflori Radix. occured at basically the same time when the herb was collected during the conventional time. This study provides evidence for the optimal collecting time of the herb.
关键词
何首乌 /
无机元素 /
动态变化 /
电感耦合等离子体质谱
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Key words
Polygoni Multiflori Radix /
inorganic element /
dynamic change /
inductively coupled plasma mass spectrometry(ICP-MS)
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中图分类号：
R284
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参考文献
[1] Ch.P(2010)Vol Ⅰ(中国药典 2010版一部).[S].2010:164-165.[2] YANG H L,GE Z Z,SUN Z X, et al. The progress in research of the pharmacology from Polygoni Multiflori Radix[J]. J Chin Med Mater(中药材), 2013,36(10): 1713-1717.[3] CAI L F,ZHONG G Y,ZHANG Q, et al. Determination of 2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucopyranoside and anthraquinon simultaneously in Polygonum multiflori of different growing stage and gathering periods by HPLC[J]. Chongqing J Res Chin Drugs Herbs(重庆中草药研究), 2011,(1):45.[4] XU Y L, DONG Q,XIAO Y C, et al.RP-HPLC Determination of anthraquinon in Polygonum multiflori of different growing stages [J]. Chin J Anal Lab(分析试验室), 2009,(S1): 327-329.[5] ZHANG Y C,SONG J P, LI J S, et al. Dynamic changes of inorganic elements in Folium Apocyni Veneti[J]. J Nat Prod, 1995, 58(3): 365-371.[6] CHEN F,ZHANG F S,LIU X H, et al. Determination of inorganic elements in Antrodia Camphorata Powder by ICP-MS [J]. J Chin Med Mater(中药材), 2014,37(2): 258-264. [7] WANG M B,XIA J, WANG X M, et al. Study on distribution and correlation of fifteen inorganic elements in ten kinds of Chinese medicinal materials [J]. Chin Pharm J(中国药学杂志), 2012,47(8):620-625.[8] LI S C. Biological effects of inorganic elements in the human body [J]. J Nanchan Educ Coll(南昌教育学院学报), 1999, (3):50. [9] TADDEL S,VIRDIS A,GHIADONIL, et al.Vitamin C improves endothelium-depetalent vasedilation by restoring nitric oxide activity in essential hypertension [J].Circulation,1998,9(4):2222-2226.[10] HUANG Z M,HUANG X. Trace elements and human health[J]. Stud Trace Elements Health(微量元素与健康研究), 2010, 27(6): 58-62.
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脚注
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基金
国家科技支撑计划项目(2011BAI13B04);江苏高校优势学科建设工程资助项目(ysxk-2014)
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