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�й�ҩѧ��־ 2014, Vol. 49 Issue (21) :1882-1884    DOI: 10.11669/cpj.2014.21.005
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TANG Li-jia, DENG Lu-lu, CHEN Xia, WANG Qin, ZHANG Jian-xin, HAO Xiao-jiang, ZHANG Yuan-hu*
The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang 550002, China

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ժҪ Ŀ�� �о�ͩҶǧ����(Stephania hernandifolia Walp.)�еĻ�ѧ�ɷ֡����� ͩҶǧ����ȫ�����������95%�Ҵ���Һ���Ȼ�����ȡ,��ѹ�����Ҵ�,Ũ��Һ��ˮϡ�ͺ�����HCl����pHֵ,ʯ������ȡ,�پ����,ʯ���ѡ����ȼ�����ȡ,�����������������������轺������Rp-18��΢��������֬CHP 20P��Sephadex LH-20����ɫ�׷������봿��,ͨ�������ʺ͹������ݽ��нṹ��������� ��ͩҶǧ�����з���õ�1�������찢�ӷ��������:9-O-ȥ�׻��������(1)������ ������1Ϊһ�µĻ����
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Abstract�� OBJECTIVE To study the chemical constituents of Stephania hernandifolia.METHODS The dried herbs of S. hernandifolia were extracted with 95% ethanol. After removal of the solvent, the residue was first partitioned between acid water and petroleum ether, then the aqueous layer was basified and extracted with chloroform to obtain crude alkaloids. Column chromatograghy on silica gel, Rp-18, MCI CHP 20P, and Sephadex LH-20 were applied for the isolation and purification of the crude alkaloids fraction. The structures were elucidated by their physicochemical properties and spectral data. RESULTS One oxoisoaporphine-type alkaloid, 9-O-demethylbianfugenine(1) was isolated from the whole plants of S. hernandifolia.CONCLUSION Compound 1 is a new compound.
Keywords�� oxoisoaporphine-type alkaloid,   9-O-demethylbianfugenine,   bianfugenine,   Menispermaceae,   Stephania hernandifolia     
�ո�����: 2014-03-26;
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TANG Li-Jia, DENG Lu-Lu, CHEN Xia etc .A New Oxoisoaporphine-type Alkaloid from Whole Plants of Stephania hernandifolia[J]  Chinese Pharmaceutical Journal, 2014,V49(21): 1882-1884
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[1] State Administration of Traditional Chinese Medicine. Zhonghua Bencao(�л����ݵڰ˾�)[M]. Vol 8, Shanghai: Scentific and Technical Publishing House,1999:203-204.[2] SEMWAL D K, BADONI R, SEMWAL R, et al. The genus Stephania(Menispermaceae):Chemical and pharmacological perspectives [J]. J Ethnopharm,2010, 132(2):369-383.[3] WANG X K, ZHAO T F. The alkaloids of Stephania [J]. West China J Pharm Sci(����ҩѧ��־), 1990, 5(2):87-93.[4] KUPCHAN S M, SUFFNESS M I, WHITE D N J, et al. Isolation and structural elucidation of 4-demethylhasubanonine, a new alkaloid from Stephania hernandifolia [J]. J Org Chem, 1968, 33(12):4529-4532.[5] TANG L J, ZHANG Y H, HAO X Y, et al. Hasubanan type alkaloids in Stephania hernandifolia [J]. China J Chin Mater Med (�й���ҩ��־), 2010, 35(15):1973-1977.[6] TANG L J, GUAN H Y, ZHANG Y H, et al. Study on the alkaloids in Stephania hernandifolia [J]. J Chin Med Mater (��ҩ��), 2010, 33(12):1881-1883.[7] TANG L J, DENG L L, HE L, et al. Three new hasubanan alkaloids from Stephania hernandifolia (Willd.) Walp [J]. Helv Chim Acta, 2013, 96(10):1930-1935.[8] HUANG Z Y, ZHANG Y H, ZHOU L, et al. Chemical constituents of Sinomenium acutum [J]. Chin Tradit Herb Drugs (�в�ҩ), 2009, 40(2):193-196.[9] TAKANI M, TAKASU Y, TAKAHASHI K. Studies on constituents of medicinal plants. XXIII.Constituents of the vines of Menispermum dauricum DC.(2) [J]. Chem Pharm Bull, 1983, 31(9):3091-3093.
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