Abstract��
OBJECTIVE To study the chemical constituents of Stephania hernandifolia.METHODS The dried herbs of S. hernandifolia were extracted with 95% ethanol. After removal of the solvent, the residue was first partitioned between acid water and petroleum ether, then the aqueous layer was basified and extracted with chloroform to obtain crude alkaloids. Column chromatograghy on silica gel, Rp-18, MCI CHP 20P, and Sephadex LH-20 were applied for the isolation and purification of the crude alkaloids fraction. The structures were elucidated by their physicochemical properties and spectral data. RESULTS One oxoisoaporphine-type alkaloid, 9-O-demethylbianfugenine(1) was isolated from the whole plants of S. hernandifolia.CONCLUSION Compound 1 is a new compound.
TANG Li-Jia,
DENG Lu-Lu,
CHEN Xia etc
.A New Oxoisoaporphine-type Alkaloid from Whole Plants of Stephania hernandifolia[J] Chinese Pharmaceutical Journal, 2014,V49(21): 1882-1884
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