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�й�ҩѧ��־ 2014, Vol. 49 Issue (16) :1393-1396    DOI: 10.11669/cpj.2014.16.007
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LIU Li1,2, DAI Yi-qun1,2, XIE Guo-yong1,2, LI Ming-liang1,2, FENG Qi-tong1, QIN Min-jian1,2*
1.Department of Resources Science of Traditional Chinese Medicines, Nanjing 210009, China;
2.State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China

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ժҪ Ŀ�� ����֦��(Salvia plebeia R. Br.)����ȡ��Ļ�ѧ�ɷֽ����о������� �����Ʊ�����ɫ�ס������轺��Sephadex LH-20��RP C18��ɫ�׵ȷ������з��봿��;���������ʼ����׷����Է���õ��Ļ�������нṹ��������� �״δ���֦�ݸ��з���õ�13��������ֱ����Ϊ��-���޴�(��-sitosterol��1)��������(ursolicacid��2)����ë�����(hispidulin��3)���پ�������(nepitrin��4)���߳�ǰ��(homoplantaginin��5)�������ؼ�������(n-butyl 3��4 dihydroxyphenyllactate��6)�������ؼ���(methyl 3��4-dihydroxyphenyllactate�� 7)���Ե��������(methyl rosmarinate��8)��salviaflaside methyl ester(9)�����Ե�������(salviaflaside��10)��(2S)-5�� 7�� 4��-���ǻ�-6-�����������ͪ-7-O-��-D-��������� �����޴�(stigmasterol�� 12)��1-O-��ʮ��������������(1-cerotoylglycerol�� 13)������ ������6��7��9��10��12��13Ϊ�״δӸ�ֲ���з���õ���
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Abstract�� OBJECTIVE To study the chemical constituents of the roots of Salvia plebeia R. Br. METHODS The constituents were isolated by various column chromatography techniques and their structures were elucidated based on spectral analysis. RESULTS Thirteen compounds were isolated from the roots of Salvia plebeia for the first time, which were elucidated as ��-sitosterol(1), ursolicacid(2), hispidulin(3), nepitrin(4), homoplantaginin(5), n-butyl 3,4-dihydroxyphenyllactate(6), methyl 3,4-dihydroxyphenyl-lactate(7), methyl rosmarinate(8), salviaflaside methyl ester(9), salviaflaside(10), (2S)-5,7,4��-trihydroxy-6-methoxyflavanone-7-O-��-D-glucopyranoside(11), stigmasterol(12) and 1-cerotoylglycerol(13). CONCLUSION Compounds 6, 7, 9, 10, 12, and 13 are isolated from Salvia plebeia for the first time.
Keywords�� Salvia plebeia,   n-butyl 3,4-dihydroxyphenyllactate,   methyl 3,4-dihydroxyphenyllactate,   salviaflaside,   structural characterization     
�ո�����: 2014-09-03;
ͨѶ���� �����,��,���� �о�����:��ҩ��Դѧ Tel/Fax:(025)86185130/(025)85301528      Email: minjianqin@163.com
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����, , ����Ⱥ�� .��֦�ݸ��Ļ�ѧ�ɷ��о�[J]  �й�ҩѧ��־, 2014,V49(16): 1393-1396
LIU Li-, , DAI Yi-Qun- etc .Chemical Constituents of Roots of Salvia plebeia[J]  Chinese Pharmaceutical Journal, 2014,V49(16): 1393-1396
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