Abstract��
To summarize advances in the toxicity and attenuation method of Tripterygium preparatum. METHODS The progresses of studies in the toxicity mechanisms and attenuation method of Tripterygium preparatum based on referring to the related literature in recent years were summarized. RESULTS Tripterygium preparatum has toxic effects in many tissues and systems. Such as hepatotoxicity, nephrotoxicity, cardiotoxic, genital system toxic, and the researches and expolrations of the attenuation method have achieved certain resulsts in dosage, direction, compatibility, processing, etc. CONCLUSION But how to apply the resulsts of these studies to reduce the toxicity in Tripterygium preparatum requires more explorations. In the aspect of attenuation and preparatum, the therapeutic index and purification processes need to further improve.
ZHANG Xin
.Research Advance in Toxicity of Tripterygium Preparatum and the Attenuation Method[J] Chinese Pharmaceutical Journal, 2013,V48(22): 1897-1901
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2013, Vol. 48 