Extraction Process of Triterpene Acids in Drugs of Leaves of Eriobotrya japonica (Thunb.) Lindl.
LI Kai-quan1, 2, TAO Hua-lei2
1.Key Laboratory for Research on Active Ingredients in Natural Medicines,Yichun 336000,China;2.Chemistry &Bioengineering College of Yichun University,Yichun 336000,China
Abstract：OBJECTIVE To study the optimum extraction condition of triterpene acids in ldregs of leaves of Eriobotrya japonica (Thunb.) Lindl. METHODS Single factor analysis and orthogonal experimental design were used to select the concentration of ethanol (A), solid-liquid ratio (B), extraction time (C), and extraction times (D) by L9(34) orthogonal test. RESULTS The concentration of ethanol was the main process factor, and extraction times was the secondary factor. The optimum condition was A2B1C3D1, which included using 90% ethanol as the extraction solvent with 7 times the amount of φ, and 80 ℃ heat back for 2 times, 1.5 h for each time. CONCLUSION Ethanol has good extraction effect for triterpene acids in loquat residue. This study provides important information for the comprehensive utilization of leaves of Eriobotrya japonica (Thunb.) Lindl. resources by pharmaceutical manufacturers.
李开泉， ，陶华蕾. 枇杷叶药渣三萜酸类成分提取工艺研究[J]. 中国药学杂志, 2013, 48(10): 805-807.
LI Kai-quan, , TAO Hua-lei. Extraction Process of Triterpene Acids in Drugs of Leaves of Eriobotrya japonica (Thunb.) Lindl.. Chinese Pharmaceutical Journal, 2013, 48(10): 805-807.
2013, Vol. 48 
