<<
[an error occurred while processing this directive]
|
[an error occurred while processing this directive]
>>
�����ζ�ӻ�ѧ�ɷ��о�
����÷ 1,2 ����־�� 1 ������ 3*
XU Xiu-mei1,2 �� LIAO Zhi-hua1 �� CHEN Min3*
(1. <>School of Life Sciences, Southwest University, Chongqing 400715, <>China; 2. <>School of Life Sciences, Linyi Normal University, Linyi 276005, <>China; 3.<> School of Life Pharmacy, Southwest University, Chongqing 400715, <>China
ժҪ Ŀ�� �о������ζ�ӣ� Schisandra neglecta A.C. Smith ���Ļ�ѧ�ɷ֡� ���� �ù轺��ɫ�ס��Ʊ� HPLC ���Ʊ� TLC ���з��룬ͨ�������ʺ������ݽ��нṹ������ ��� �ӵ����ζ�ӵľ����з���õ� 9 ��ľ֬�غ� 1 �������ᣬ�ֱ������������� R ������ζ�ӷ��ң����� - �� - ������ L1 ���������������� P ��������˳���������� P �������������� R ������������ζ���أ�����������ζ���ᣨ������������� O �������������� O �������� ���� ���л�������״δӸ�ֲ���з���õ���
Abstract��
OBJECTIVE To study the chemical constituents of Schisandra neglecta. METHODS The chemical constituents were isolated by silica gel , prep-HPLC and prep-TLC methods. And their structures were elucidated by physical-chemical and spectroscopic methods. RESULTS Nine dibenzocyclooctadiene lignans, acetylgomisin R (��), schisanhenol B (��), (-)-gomisin L1 (��), benzoylgomisin P (��), tigloylgomisin P (��), gomisin R (��), kadsurin (��), epigomisin O (��), gomisin O (��)and one kadsuric acid(��) were isolated from the stem of S. neglecta. CONCLUSION All compounds were isolated from the plant for the first time.
XU Xiu-mei,
LIAO Zhi-hua
. Studies on Chemical Constituents of Schisandra neglecta A.C. Smith[J] Chinese Pharmaceutical Journal, 2009,V44(23): 1769-1772
��
[1]
CHEN Y G, WANG P, LIN Z W, et al. Dibenzocyclooctadiene lignans from Kadsura angustifolia [J]. Phytochemistry, 1998, 48(6):1059-1062.
[2]
CHEN D F, ZHANG S X, CHEN K, et al. Two new lignans , interiotherins A and B , as anti-HIV principles from Kadsura interior [J ] . J Nat Prod, 1996 , 59(11):1066-1068.
[3]
KUO Y H, KUO L M, CHEN C F. Four new C19 homolignans, schiarisanrins A, B and D and cytotoxic schiarisanrin C from <>Schizandra arisanensis[J]. J Org Chem, 1997, 62(10): 3242-3245.
CHEN Y G, QIN G W, XIE Y Y. Dibenzocyclooctadiene lignans from schisand a propinqua [J] . Chem J Chin Univ ( �ߵ�ѧУ��ѧѧ�� ), 2001, 22(9):1518-1520.
[6]
IKEYA Y, MIKI E, OKADA M, et al. Benzoylgomisin Q and P, two new lignans from Schisandra<>sphenanthera Rehd. Et Wils. [J]. Chem Pharm Bull, 1990, 38(5):1408-1411.
[7]
IKEYA Y, TAGUCHI H, YOSIOKA I. The constituents of schizandra chinensis baill. ��. The sturctures of ��-schizandrin and four new lignans, (-)-gomisins L1 and L2, (��)-gomisin M1 and (+)-gomisin M2[J]. Chem Pharm Bull, 1982, 30(1):132-139.
[8]
IKEYA Y, TAGUCHI H, YOSIOKA I. The constituents of schizandra chinensis baill XII. isolation and structure of a new lignan, gomisin R, the absolute structure of Wuweizisu C and isolation of schisantherin D [J]. Chem Pharm Bull, 1982, 30(9):3207-3211.
[9]
CHEN D F, XU G J, YANG X W. et al. Dibenzocyclo-octadiene lignans from Kadsura<>heteroclite [J]. Phytochemistry,1992, 31(2):629-632.
[10]
YAMADA Y, HSU C S, IGUCHI K, et al. Structure of kadsuric acid. A new seco-triterpenoid from Kadsura<>japonica Dunal [J]. Chem Lett , 1976, 1307-1310.
[11]
IKEYA Y, TAGUCHI H, YOSIOKA I. et al . The constituents of schizandra chinensis baill. ��. The strutures of four new lignans, gomisin N, gomisin O, epigomisin O and gomisin E, and transformation of gomisin N to deangeloylgomisin B [J]. Chem Pharm Bull, 1979, 27(11):2695-2709.