Abstract��
OBJECTIVE To develop GC/MS method in detect plasticizers in compound aluminum hydroxide tablets adsorbed from pharmaceutical packaging. METHODS The column�� HP-5MS silica capillary column (30 m��0.25 ��m��0.25 mm) was used�� Ion source temperature was 230 �棻 Quadrupole temperature was 150 �棻 The total ion scanning rang�� m/z 50��500. RESULTS The diethylhexyl phthafate linearity was in the range of 0.5-20.0 ��g��mL-1 with a regression coefficient of 0.999 0. The average recovery of this method was 98.8%�� and RSD was 1.4%. The RSD of intra-day and inter-day was 2.8% and 3.7% respectively. CONCLUSION This method is specificity�� sensitive�� and can be applied to detect and research DEHP which may be adsorbed or penetrated into drugs.
2012, Vol. 47 
