中国药学杂志
    
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�й�ҩѧ��־ 2010, Vol. 45 Issue (8) :571-573    DOI:
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1.���ݴ�ѧҩѧԺ�� ���� 550002��2.����ʡ�й���ѧԺ��Ȼ���ﻯѧ�ص�ʵ���ң����� 550002��
YE Lin-hu1��2�� YANG Xiao-sheng1��2*�� MA Lin2�� HAO Xiao-jiang2
1.School of Pharmacy�� Guizhou University�� Guiyang 550002��China; 2. Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences�� Guiyang 550002�� China

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ժҪ Ŀ�� ��չë�����˻�ѧ�ɷ��о���Ϊ�俪�������ṩ���ݡ����� ���������75%�Ҵ���ȡ�����轺��������ɫ�׷��룬ͨ��NMR��MS���׷�����ȷ���ṹ����� �ֵ�11��������ֱ����Ϊ����֬�ᣨbetulinic acid����)������֬����betulin����)����չ���(oleanolic acid����)���ܹ���(ursolic acid�� ��)��2��-�ǻ��ܹ���(2��-hydroxyursolic acid�� ��)��������(cirsimartin�� ��)��ܾ����( genkwanin����)����-���޴�(��-sitosterol����)�����ܲ���(daucosterol����)��������(arachidic acid����)�����ǻ����������(methy-p-hydroxybenzoate�� ��)������ ������񡢢򡢢󡢢�Ϊ�״δӸ�ֲ���з���õ���������Ϊ�״δӸ���ֲ���з���õ���
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Abstract�� OBJECTIVE To investigate the chemical constituents of Isodon eriocalyx.and provide evidences for further utility of this abundant plant resource. METHODS The 75% aqueous ethanol was used for extracting the plant material�� chromatography with silica gel and Sephadex LH-20 for purifying components�� and analysis of spectroscopic evidences for identifying chemical structures. RESULTS Eleven non-diterpenoid constituents were elucidated as betulinic acid (��)�� betulin (��)�� oleanolic acid (��)�� ursolic acid (��)�� 2��-hydroxyursolic acid (��)�� cirsimartin (��)�� genkwanin (��)�� ��-sitosterol (��)�� daucosterol (��)�� arachidic acid (��)�� methy-p-hydroxybenzoate (��). CONCLUSION Compound�� �� �� and �� were isolated from this plant for the first time. The compound �� and �� were obtained firstly from the genus Isodon.
Keywords�� Isodon eriocalyx,   non-diterpenoid constituents,   arachidic acid,   methy-p-hydroxybenzoate     
�ո�����: 2012-01-01;
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.���ݲ�ë�������зǶ��ƻ�ѧ�ɷ�[J]  �й�ҩѧ��־, 2010,V45(8): 571-573
.Non-diterpenoid Constituents from Isodon eriocalyx Distributed in Guizhou Province[J]  Chinese Pharmaceutical Journal, 2010,V45(8): 571-573
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