摘要
目的 研究报春花科报春花属植物胭脂花（Primula maximowiczii Regel的化学成分。方法 运用多种色谱方法，从胭脂花全草中分离得到9个化合物，通过理化性质和波谱数据鉴定化合物的结构。结果 分离得到的化合物结构为：2-樱草糖基-5-甲氧基-苯乙酮(1，芍药交酯(2，4-羟基-苯乙酮(3，云杉素(4，2-O-β-D-葡萄糖基-4-甲氧基-苯甲酸甲酯(5，4-樱草糖基-苯乙酮(6，山柰酚3-O-(2-O-α-L-鼠李糖基-6-O-β-D-木糖基-β-D-葡萄糖苷(7，山柰酚3-O-新橘皮糖苷(8，槲皮素3-O-龙胆双糖苷(9。结论 化合物1为新化合物，化合物2~6、9为首次从该属植物中分离得到，化合物7、8为首次从胭脂花中分离得到。
Abstract
OBJECTIVE To study the chemical constituents of Primula maximowiczii Regel. METHODS Nine compounds from the aerial part of P. maximowiczii were obtained by column chromatography. Their structures were elucidated by spectroscopic data and physical-chemical properties. RESULTS Nine comounds were isolated and identified as 2-primeverosyl-5-methoxy-acetophenone(1，peonolide(2，4-hydroxy-acetophenone(3，picein(4，2-O-β-D-glucopyranosyl-4-methoxy-methylbenzoate(5，4-primeverosyl-acetophenone(6，kaempferol 3-O-(2-O-α-L-rhamnopyransoyl-6-O-β-D-xylopyranosyl-β-D- glucopyranoside(7，kaempferol 3-O-neohesperidoside(8 and quercetin 3-O-gentiobioside(9. CONCLUSION Compund 1 is a new one. Compound 2-6 and 9 are isolated for the first time from Primula. Compound 7 and 8 are obtained from Primula maximowiczii Regel for the first time.
关键词
胭脂花 /
2-樱草糖基-5-甲氧基-苯乙酮 /
芳香酸酯苷
{{custom_keyword}} /
Key words
Primula maximowiczii Regel /
2-primeverosyl-5-methoxy-acetophenone /
aromatic acid ester glycoside /
flavonol glycoside
{{custom_keyword}} /
曲功霖 张海鸣 邓志威 孔德云 耿珠峰 杜树山.
胭脂花化学成分的研究Ⅲ[J]. 中国药学杂志, 2011, 46(2): 93-97
QU Gong-lin;ZHNG Hi-ming;DENG Zhi-wei;KONG De-yun;GENG Zhu-feng;DU Shu-shn.
Study on Chemical Constituents of Primula maximowiczii Regel： Part III[J]. Chinese Pharmaceutical Journal, 2011, 46(2): 93-97
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] The editorial board of Chinese material medium. Chinese Materia Medica(中华本草[M]. Vol. 16. Shanghai：Shanghai Scientific & Technical Publishers，1999： 120-121.
[2] MA Y Q．Flora Intramongolica(内蒙古植物志[M]．Tomus 5．Huhhot：Typis Intramongo-licae Popularis，1980： 27-28．
[3] QU G L， OUYANG J， KONG D Y， et al. Chemical constituents of Primula maximowiczii Regel[J]．Chin Tradit Herb Drugs(中草药，2007，38(9： 1308-1310.
[4] QU G L， OUYANG J， KONG D Y， et al. Studies on chemical constituents of Primula maximowiczii Regel II [J]．Chin Pharm J(中国药学杂志，2008，43(17： 1300-1304.
[5] KUWAJIMA H，SHIBANO N，BABA T，et al. An acetophenone glycoside from Exacum affine[J]. Phytochemistry，1996，41(1： 289-292.
[6] SREBOTNIK E，JENSEN K A，KAWAI S，et al. Evidence that ceriporiopsis subvermispora degrades nonphenolic lignin structures by a one-electronoxi- dation mechanism[J]. Appl Environ Microbiol，1997，63(11： 4435-4440.
[7] SCHROEDER C，LUTTERBACH R，STOECKIGT J. Preparative biosynthesiss of natural glucosides and fluorogenic substrates for β-glucosidases followed by in vivo 13C-NMR with high density plant cell cultures[J]. Tetrahedron，1996，52(3： 925-934.
[8] WAGNER G，KUHMSTEDT H. Phenol glycosides. XVIII. Fermentative hydrolysis of β-D-glucopyranosides of the resorcylic acid series[J]. Arch Pharm，1960，29(3： 428-441.
[9] LI J，KADOTA S，KAWATA Y，et al. Constituents of the roots of Cynanchum bungei Decne. Isolation and structures of four new glucosides，bungeiside A，B，C，and D[J]. Chem Pharm Bull，1992，40(12： 3133-3137.
[10] SHAO Y，LI Y L，ZHOU B N. Phenolic and triterpenoid glycosides from Aster batangensis[J]. Phytochemistry，1996，41(6： 1593-1598.
[11] FICO G，RODONDI G，FLAMINI G，et al. Comparative phytochemical and morphological analyses of three Italian Primula species[J]. Phytochemistry，2007，68(12： 1683-1691.
[12] KAZUMA K，NODA N，SUZUKI M. Malonylated flavonol glycosides from the petals of Clitoria ternatea[J]. Phytochemistry，2003，62(2： 229-237.
{{custom_fnGroup.title_cn}}
脚注
{{custom_fn.content}}
PDF(580 KB)
