摘要
目的 研究金银花(Lonicerae Japonicaer Flos化学成分。方法 利用Diaion HP-20，Toyopearl HW-40，硅胶柱等柱色谱技术进行分离纯化，根据化合物的理化性质和光谱数据鉴定结构。结果 分离并鉴定了11个化合物的结构： 对羟基苯酚(Ⅰ，1，2，4-苯三酚(Ⅱ，原儿茶酸(Ⅲ，3-(3，4-二羟基苯基丙酸(Ⅳ，4-羟基桂皮酸(Ⅴ，4-羟基桂皮酸甲酯(Ⅵ，咖啡酸甲酯(Ⅶ，芹菜素(Ⅷ，3′-甲氧基木犀草素(Ⅸ，5，3′-二甲氧基木犀草素(Ⅹ，木犀草素-5-O-β-D-葡萄糖苷(Ⅺ。结论 化合物Ⅰ～Ⅺ均为首次从该植物中分离得到。
Abstract
OBJECTIVE To study the chemical constituents of Lonicerae Japonicaer Flos. METHODS The compounds were isolated and purified by Diaion HP-20， Toyopearl HW-40， and silica gel column chromatography. The structures were identified on the basis of spectral data and physiochemical properties. RESULTS Eleven compounds were isolated and identified as： p-hydroxy-phenol (Ⅰ， 1， 2， 4-benzenetri (Ⅱ， protocatechuic acid (Ⅲ， 3-(3， 4-dihydroxyphenyl propionic acid (Ⅳ， 4-hydroxy cinnamie acid (Ⅴ， 4-hydroxy cinnamie acid methyl (Ⅵ， caffeic acid methyl ester(Ⅶ， apigenin(Ⅷ， 3′-methoxy luteolin(Ⅸ， 5， 3′-dimethoxy luteolin (Ⅹ， luteolin-5-O-β-D-glucopyranoside (Ⅺ. CONCLUSION CompoundsⅠ-Ⅺ were isolated from this plant for the first time.
关键词
金银花 /
化学成分 /
结构鉴定
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Key words
Lonicerae Japonicaer Flos /
chemical constituents /
structure identification
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冯卫生 陈欣 郑晓珂 张春磊 李丹丹.
金银花化学成分研究[J]. 中国药学杂志, 2011, 46(5): 338-340
FENG Wei-sheng;CHEN Xing;ZHENG Xio-ke;ZHNG Chun-lei;LI Dn-dn.
Study on Chemical Constituents of Lonicerae Japonicae Flos [J]. Chinese Pharmaceutical Journal, 2011, 46(5): 338-340
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参考文献
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