摘要
目的对圆锥铁线莲全草的乙醇提取物进行分离和结构鉴定。方法通过硅胶和凝胶柱色谱分离;利用多种波谱技术并结合酸水解方法鉴定其化学结构。结果分离鉴定了7个化合物,分别为正二十三醇(Ⅰ)、正二十七烷酸(Ⅱ)、3,5,7,3′-四羟基黄酮(Ⅲ)、5,7,3′,5′-四羟基二氢黄酮(Ⅳ)、芹菜素(Ⅴ)、木犀草素(Ⅵ)和豆甾醇-3-O-β-D-葡萄糖苷(Ⅶ)。结论化合物Ⅰ~Ⅳ为首次从铁线莲属中分离得到。
Abstract
OBJECTIVE To study the constituents in the whole plants of Clematis terniflora DC.METHODS Column chromatographic methods (including silica gel and Sephadex LH-20) were used to separate constituents whose structures were elucidated by ESI-MS,NMR spectral data and hydrolysis methods.RESULTS Seven compounds were isolated and elucidated as tricosanol (Ⅰ),heptacosanoic acid (Ⅱ),3,5,7,3′-tetrahydroxyflavone (Ⅲ),5,7,3′,5′-tetrahydroxy-dihydroflavone (Ⅳ),apigenin (Ⅴ),luteolin (Ⅵ) and stigmasterol-3-O-β-D-glucopyranoside (Ⅶ). CONCLUSION Compound Ⅰ~Ⅳ are isolated from Clematis genus for the first time.
关键词
圆锥铁线莲 /
正二十三醇 /
5 /
7 /
3′ /
5′-四羟基二氢黄酮
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Key words
Clematis terniflora /
tricosanol /
5 /
7 /
3′ /
5′-tetrahydroxy-dihydroflavone
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孙凤;张琳;田景奎;程翼宇;肖培根.
圆锥铁线莲化学成分的研究[J]. 中国药学杂志, 2007, 42(02): 102-103
SUN Feng;ZHNG Lin;TIN Jing-kui;CHENG Yi-yu;XIO Pei-gen.
Studies on Chemical Constituents of Clematis terniflora [J]. Chinese Pharmaceutical Journal, 2007, 42(02): 102-103
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参考文献
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脚注
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