摘要
目的定性、定量分析赤芍中挥发性成分、方法利用气相色谱-质谱(GC-MS)进行检测,再通过直观推导式演进特征投影(HELP)法对产生的二维色谱-质谱数据进行解析,得到各组分的纯色谱曲线和质谱,根据其保留时间和质谱,在质谱库中进行相似检索,实现对组分的定性,再用总体积积分法进行定量。结果共分辨出57个色谱峰,通过质谱库对分辨的纯组分进行检索,鉴定了其中38个组分,占赤芍挥发成分总合量的95.21%。结论赤芍主要挥发成分为(Z,Z)-9,12-十八碳二烯酸,正十六碳酸和水杨醛。
Abstract
OBJECTIVE To analyze the volatile chemical components of Radix Paeoniae Rubra(RPR).METHODS Gas chromatography-mass spectrometry(GC-MS),heuristic evolving latent projections(HELP)method,and overall volume,integration methods were used.RESULTS Thirty- eight volatile chemical components in RPR were determined,accounting for 95.21% of volatile chemical components of RPR.CONCLUSION The mail volatile chemical components of RPR are(Z,Z)-9,12-octadecadienoic acid,n-hexadecanoic acid and 2-hydroxy-benzaldehyde.
关键词
赤芍 /
挥发性成分 /
气相-质谱联用 /
直观框导式演进特征投影法
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Key words
Radix Paeoniae Rubra /
volatile chemical components /
GC-MS /
heuristic evolving latent projections method
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李晓如;梁逸曾;杨辉;郭方遒.
赤芍挥发性成分的GC-MS与直观框导式演进特征投影法分析[J]. 中国药学杂志, 2006, 41(10): 738-740
LI Xio-ru;LING Yi-zeng;YNG Hui;GUO Fng-qiu.
Analysis of Volatile Chemical Components in Radix Paeoniae Rubra by GC-MS and Heuristic Evolving Latent Projections Method [J]. Chinese Pharmaceutical Journal, 2006, 41(10): 738-740
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参考文献
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脚注
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基金
国家自然科学基金(2017503，20235020)
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