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ժҪ Ŀ�� ۲��ҩ�Ƽ��(��ֲ��ή�� Potentilla anserinal.��ȡ��õ��Ҫ��Գɷ֣��FGN)��С��ʵ��Ը��˵ı��ã��۸��ܵ��˻ƽ�ø��Ч�� û�ѧ��Ȼ�̼(CCl₄)��(ANIT)��С��ˣ��ⶨ��ָ�겢�۲첡��֯ѧ�ı䡣�� 0.165��0.0825 g��kg^-1��CCl₄��µ�С��Ѫ��ת��ø(ALT)��(P��0.01)��ANTT��µ�С��Ѫ��ܵ��(SB)��(P��0.01)��0.04125 g��kg^-1��ָ��û��Ӱ�졣�� ܶ�С��ʵ��Ը��˾��Եı��á�

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Abstract�� OBJECTIVE To study the protective effects of Fuganneng (FGN) on experimental hepatic injury in mice,and evaluate its effects of rejected jaundice and reduced enzyme.METHDOS The model of hepatic injury was induced by CCl₄ and ANIT.The biochemical indexes were determined and the histopathological changes were observed.RESULTS FGN 0.165 and 0.0825 g��kg^-1 significantly inhibited the rising of serum alanine transaminase (ALT) and the serum bilirubin (SB) induced by CCl₄ and ANIT respectively.(P��0.01).FGN 0.4125 g��kg^-1had no effects on the biochemical indexes mentioned above.CONCLUSION FGN had significant protective effects on experimental hepatic injury in mice.

Keywords�� FGN, experimental injury, CCl₄ , ANIT

�ո��: 2000-09-07;

��:��塱��ҩ��⣨96-901-05-160��

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.��ҩ�Ƽ��ܶ�С��ʵ��Ը��˵ı��[J] �й�ҩѧ��־, 2001,V36(07): 448-450

.Protective effects of Fuganneng(FGN) on experimental hepatic injury in mice[J] Chinese Pharmaceutical Journal, 2001,V36(07): 448-450

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