喹诺酮类药物不良反应及药物相互作用

连儒强;张立蘅;吴照刚;

中国药学杂志 ›› 2002, Vol. 37 ›› Issue (02) : 108-110.

中国药学杂志 ›› 2002, Vol. 37 ›› Issue (02) : 108-110.
综述

喹诺酮类药物不良反应及药物相互作用

  • 连儒强;张立蘅;吴照刚;
作者信息 +
文章历史 +

摘要

目的:介绍喹诺酮类药物不良反应及药物相互作用。方法:通过查阅文献总结多年来不良反应报告及药物作相互作用。结果:该类药物在临床应用中,在骨骼、皮肤、心脏、中枢系统等均报告出现不良反应,并与多种药物发生相互作用。结论:喹诺酮类药物为临床常用抗感染药,对其不良反应及药物相互作用应尤为引起注意[1.2]

关键词

喹喏酮 / 不良反应 / 药物相互作用

引用本文

导出引用
连儒强;张立蘅;吴照刚;. 喹诺酮类药物不良反应及药物相互作用[J]. 中国药学杂志, 2002, 37(02): 108-110

参考文献

1 方翼.3种氟喹诺酮类药物抗生素后效应的研究[J].中国抗生素杂志,1997;22(1):67 2 汪复. 氟喹诺酮类药物临床应用进展[J]. 中华内科杂志, 1999, 38:65. 3 Schaad UB, Stoupic C, Wedgwood KJ, et al. Clinical radiologic and magnetic resonance monitoring for skeletal toxicity in pediatric patients with cystic fibrosis receiving a threemonth course of ciprofloxacin[J]. Pediatr Infect Dis J, 1991, 10:723. 4 Rubio TT. Ciprofloxacin in the treatment of pseudomonas infection in children with cystic fibrosis[J]. Diag Microbiol Infect Dis, 1990, 13:153. 5 Schaad UB. Use of fluorquinolones in pediatrics:consensus report of an international society of chemotherapy commission[J]. Pediatr Infect Dis J, 1995, 14:1. 6 Schaad UB, Sander E, Wedgwood J, et al. Worphologic studies for skeletal toxicity after prolonged ciprofloxacin therpy in two juvenile cystic fibrosis patients[J]. Pediatr Infect Dis J, 1999, 37:47-48. 7 陶然.司帕沙星致日光性皮炎1例[J].中国新药杂志,1999,8(6):369. 8 吴荷芳.氟喹诺酮类药物不良反应分析[J].中国医院药学杂志,1999,19(12):765. 9 Paton JH,Reeves DS.Fluoroquinolone aptibiotics,microbiology,pharmacokinetics and clincial use[J].Drugs,1988,36(2):193. 10 戴自英.实用抗菌药物学[M].第2版.上海:上海科学技术出版社,1998.278. 11 聂青和,张开瑞.氟喹诺酮类抗菌药物不良反应的临床观察[J].中级医刊,1993,5:45. 12 陈术辉.喹诺酮类抗菌药的联合药与不良反应[J].湖南医学,1997,14(6):369. 13 吴荷芳,王洪泽.氟喹诺酮类药物不良反应分析.中国医院药学杂志,1999,19(12):65. 14 徐永昭.氧氟沙星的药物相互作用[J].辽宁医学杂志,1996,10(2):97. 15 徐镜海.环丙沙星与其它药物的相互作用[J].武汉医学杂志,1996,20(3):178. 16 刘洪云.环丙沙星合并用药的相互作用[J].中国医院药学杂志,1996,16(10):444. 17 Matuschka PR,Vissing RS.Clinafloxacin theophylline drug interac-tion[J].Ann Rharmacother,1995,29(4):378. 18 Sarkar M,Polk RE,Guzelian PS,et al.In vitro effect of fluoro-quinolones on theophylline metabolism in human liver microsomes[J].Antimicrob Agents chemother,1990,34(4):594. 19 Marchbanks CR.Drug interactions with fluoroquinolones[J].Pharmacothera-py,1993,13(2pt2):235. 20 Hasegawa T,Nadai M,Apichartpichean R,et al.Pharmacokinetic characteristics of N7-substituted theophylline derivatives and their interaction with quinolone in rats[J].J Pharm Sci,1991,80(10):962. 21 Fuhr U,Wolff T,Harder S,et al.Quinolone inhibition of cytochrome P-450-dependant caffeine metabolism in human liver microsomes[J].Drug Metab Dispos,1990,18(6):1005. 22 Deppermann LM,Lode H,Fluoroquinolones:interaction profile during enteral absorption[J].Drugs,1993,45 Suppl 3:65. 23 Deppermann LM,Lode H,Hoffken G,et al.Infucence of food ranitidine and antacids on the enteral absoption of ofleroxacin[J].J Antimicrob chemother.submitted.1993,a 24 Janknegt R.Drug interaction with quinolones[J].J Antimicrob Chemother,1990,26 Suppl D:7~29. 25 Lazzaroni m,Imbimbo BP,Bargiggia S,et al.Effects of magnesium-aluminum hydroxide antacid on absoption of rufloxacin.Antimicrob Agents Chemother[J].1993,37(10):2212. 26 Marshall AJ, Piddock LJ,Interaction of divalent cations, quinolones and bacteria[J].J-Antimicrob-Chemother,1994,34(4):465. 27 Deppermann KM,Lode H,Hoffken G,et al.Infuence of ferrous-sulfate on the bioavailability of ciproxacin and of loxacin[J].Eur J Microbio,1993b.

30

Accesses

0

Citation

Detail

段落导航
相关文章

/