摘要
目的研究小飞蓬的化学成分。方法应用溶剂法进行提取,采用硅胶柱色谱和凝胶柱色谱Sephadex LH-20进行分离纯化,通过理化方法和波谱数据分析进行结构鉴定。结果从体积分数70%乙醇提取物中分离并鉴定了12个化合物,分别为α-香树脂醇(Ⅰ)、β-香树脂醇(Ⅱ)、β-谷甾醇(Ⅲ)、表木栓醇(Ⅳ)、齐墩果酸(Ⅴ)、菠甾醇-3-O-葡萄糖苷(Ⅵ)、3,5,7,3′,4′-五羟基黄酮(Ⅶ)、槲皮素-3-O-α-L-鼠李糖苷(Ⅷ)、芦丁(Ⅸ)、野黄芩苷(Ⅹ)、黄芩苷(Ⅺ)、绿原酸(Ⅻ)。结论12个化合物均为首次从该植物中分离得到。
Abstract
OBJECTIVE To study the chemical components from Erigeron canadensis. METHODS The isolation and purification were carried out on silica gel column and Sephadex LH-20. The structures were elucidated on the basis of chemical evidences and spectral analysis. RESULT Twelve compounds were isolated and their structures were identified as αasamyrin(Ⅰ), β-amyrin (Ⅱ), β-sitosterol(Ⅲ)、epifriedelinol(Ⅳ), oleanolic acid(Ⅴ), spinasterol-3-O-β-D-glucopyranoside(Ⅵ), 3,5, 7,3′,4′-pentahydroxyflavone(Ⅶ), quercetin-3-O-α-L-rhamnose(Ⅷ), rutin(Ⅸ), scutellarin(Ⅹ), baical(iⅪ) and chlorogenic acid(Ⅻ). CONCLUSION All the twelve compunds are isolated from the title plant for the first time.
关键词
小飞蓬 /
飞蓬属 /
三萜 /
黄酮
{{custom_keyword}} /
Key words
Erigeron canadensis /
Erigeron /
triterpene /
flavone
{{custom_keyword}} /
邵帅;严铭铭;毕胜男;黄耀玲;付影超;徐洋.
小飞蓬化学成分的研究[J]. 中国药学杂志, 2009, 44(14): 1053-1055
SHO Shui;YN Ming-ming;I Sheng-nn;HUNG Yo-ling;FU Ying-cho;XU Yng.
Chemical Constituents of Erigeron canadensis[J]. Chinese Pharmaceutical Journal, 2009, 44(14): 1053-1055
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
[1] LI R，CHEN Y L，SHI T. Flora of China（中国植物志）[M]. Vol.74， Beijing：Science Press，1985：295.
[2] LV J W，ZHANG C Z，LI C，et al. Studies on identification of triterpenes from Soroseris gillii Stebb. [J]. Chin Tradit Herb Drugs(中草药)，2006，37(3)：349.
[3] YUAN J Z，SU Q S. A study on the chemical constituents of the leaves of Quercus acutissma Carruth [J]. J Shenyang Pharm Univ(沈阳药科大学学报)，1999，16（1）：601-602.
[4] FORGACS P，PROVOST J. Olaxoside，a saponin from Olax andronensis，Olax glabriflora and Olax psittacorum[J]. Phytochem- istry，1981，20(7)：1689-1691.
[5] XIONG J，ZHOU J，DAI H F，et al. Chemical constituents from Phytolacca polyandra[J]. Acta Bot Yunnanica(云南植物研究)，2002，24（3）：401-405.
[6] LI Y M，WANG T Z，WANG Z X. Studies on chemical constituents in dried buds of Lonicera similis Hemsl.[J]．China J Chin Mater Med(中国中药杂志)，2001，26(1)：45-47.
[7] YU D Q，YANG J S. Chemical Analysis of Manual：Nuclear Magnetic Resonance Spectroscopy（分析化学手册：核磁共振波谱分析）[M]. Beijing：Chemical Industry Press，1999：820.
[8] LI Y I，LUO H F，WANG Y L，et al. Studies on the chemical constituents of flavonoids from Polygonum capitatum[J]. Chin Pharm J（中国药学杂志），2000，35(5)：300.
[9] LIANG Q L，DING L S. Chemical study on the leaves of Raisin Tree(Hovenia acerba) （Ⅰ）[J]. Chin Tradit Herb Drugs(中草药)，1996，27（10）：581-583.
[10] FENG Y L，XU L Z，YANG S L，et al. Chemical constituents isolated from flowers of Althaea rosea（Ⅰ）[J]. Chin Tradit Herb Drugs(中草药)，2005，36（11）：1610-1612.
[11] XIANG T，WU L J，DONG M，et al. Studies on the chemical constituents of Lonicera bournei Hemsl.（Ⅰ）[J]. Chin J Med Chem(中国药物化学)，1998，8（1）：44-45.
[12] JIA L Y，SUN Q S，HUANG S W. Isolation and identification of flavonoids from Chrysanthemum morifolium Ramat [J]. Chin J Med Chem(中国药物化学)，2003，13（3）：159-161.
{{custom_fnGroup.title_cn}}
脚注
{{custom_fn.content}}
基金
国家科技支撑项目(2007BA138B05)
{{custom_fund}}
