黑骨藤化学成分的研究

徐冉 张援虎 赵延涛

中国药学杂志 ›› 2011, Vol. 46 ›› Issue (11) : 823-825.

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中国药学杂志 ›› 2011, Vol. 46 ›› Issue (11) : 823-825.
论著

黑骨藤化学成分的研究

  • 徐冉1,2,张援虎2*,赵延涛2
作者信息 +

Study on Chemical Constituents of Periploca forrestii Schlecht.

  • XU Ran1,2,ZHANG Yuan-hu2*,ZHAO Yan-tao2
Author information +
文章历史 +

摘要

目的 研究黑骨藤的化学成分。方法 应用硅胶、MCI、Sephadex LH-20、RP-18柱色谱进行分离、纯化,根据理化常数和光谱分析鉴定结构。结果 从黑骨藤氯仿萃取部分分离鉴定了13个单体化合物:β-谷甾醇(1,熊果酸(2,大黄素(3,臭矢菜素A(4,臭矢菜素B(5,胡萝卜苷(6,滇杠柳苷Ⅰ(7,杠柳苷(8,2α,3β,5,24-四羟基-齐墩果-12-烯-28-羧酸(9,大黄素-8-甲醚(10,北五加皮苷E(11,香草酸(12,3,5-二甲氧基-4-羟基苯甲酸(13。结论 化合物4、5、9、12、13为首次从黑骨藤中分离鉴定。

Abstract

OBJECTIVE To study the chemical constituents of Periploca forrestii Schlecht. METHODS Various chromatographic techniques were used to isolate the constituents,and their structures were identified by spectral and chemical methods. RESULTS Thirteen compounds were isolated and identified as β-sitosterol (1,ursolic acid (2,emodin (3,cleomiscosin A (4,cleomiscosin B (5,daucosterol (6,periforosideⅠ(7,periplocin (8,2α,3β,5,24-tetrahydroxy-olean-12-en-28-oic acid (9,questin (10,glycoside E (11,vanillic acid (12,and 3,5-dimethoxy-4-hydroxybenzoic acid(13. CONCLUSION Compounds 4,5,9,12 and 13 are isolated for the first time from P. forrestii Schlecht..

关键词

黑骨藤 / 臭矢菜素 / 熊果酸 / 3 / 5二甲氧基-4-羟基苯甲酸 / 化学成分

Key words

Periploca forrestii Schlecht. / cleomiscosin / ursolic acid / 3 / 5-dimethoxy-4-hydroxybenzoic acid / chemical constituents

引用本文

导出引用
徐冉 张援虎 赵延涛. 黑骨藤化学成分的研究[J]. 中国药学杂志, 2011, 46(11): 823-825
XU Rn;ZHNG Yun-hu;ZHO Yn-to . Study on Chemical Constituents of Periploca forrestii Schlecht.[J]. Chinese Pharmaceutical Journal, 2011, 46(11): 823-825

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