短瓣金莲花水溶性化学成分研究

吴丽真 许旭东 杨峻山

中国药学杂志 ›› 2011, Vol. 46 ›› Issue (10) : 745-746.

PDF(400 KB)
中国药学杂志
PDF(400 KB)
中国药学杂志 ›› 2011, Vol. 46 ›› Issue (10) : 745-746.
论著

短瓣金莲花水溶性化学成分研究

  • 吴丽真，许旭东*，杨峻山
作者信息 +

Chemical Constituents of Water Soluble Fraction of Trollius ledebouri Reichb

  • WU Li-zhen，XU Xu-dong*，YANG Jun-shan
Author information +
文章历史 +

摘要

目的 研究短瓣金莲花水溶性部位的化学成分。 方法 采用硅胶柱色谱、Sephadex LH-20凝胶色谱、中压及高压半制备色谱等手段分离，并运用现代光谱技术鉴定化合物结构。结果 从短瓣金莲花水部分分离得到4个化合物，分别鉴定为： 2-(3，4-dihydroxyphenyl-2-hydroxyethyl-O-β-D-glucopyranoside(Ⅰ ，2-(3，4-dihydroxyphenyl-ethyl-O-β-D-glucopyranoside（Ⅱ，3，5-dihydroxyphenethyl alcohol 3-O-β-D-glucopyranoside（Ⅲ，菊苣苷 (cichoriin，Ⅳ。 结论 化合物Ⅰ~Ⅳ均为首次从本属植物中分离得到，其中化合物Ⅰ为新的天然产物。

Abstract

OBJECTIVE To study the chemical constituents of Trollius ledebouri Reichb. METHODS The constituents of Trollius ledebouri were isolated and purified by means of various chromatography techniques，and their structures were identified by modern spectral measures. RESULTS Four components were isolated from the Trollius ledebouri Reichb，and identified as 2-(3，4-dihydroxyphenyl-2-hydroxyethyl-O-β-D-glucopyranoside，2-(3，4-dihydroxyphenyl-ethyl-O-β-D-glucopyranoside，3，5-dihydroxyphenethyl alcohol 3-O-β-D-glucopyranoside and cichoriin，respectively. CONCLUSION All compounds are isolated from Trollius for the first time，of which compound Ⅰ is a new natural product.

关键词

短瓣金莲花 / 毛茛科 / 2-(3 / 4-dihydroxyphenyl-2-hydroxyethyl -O-β-D-Glucopyranoside / 化学成分

Key words

Trollius ledebouri Reichb / Ranunculaceae / 2-(3 / 4-dihydroxyphenyl-2-hydroxyethyl alcohol-O-β-D-glucopyranoside / chemical components

引用本文

EndNote

Ris (Procite)

Bibtex

导出引用
吴丽真 许旭东 杨峻山. 短瓣金莲花水溶性化学成分研究[J]. 中国药学杂志, 2011, 46(10): 745-746
WU Li-zhen;XU Xu-dong;YNG Jun-shn. Chemical Constituents of Water Soluble Fraction of Trollius ledebouri Reichb[J]. Chinese Pharmaceutical Journal, 2011, 46(10): 745-746

参考文献


[1] Flora of China Editor Committee of Chinese Academy of Science. Flora of China (中国植物志 [M]. Beijing： Science and Technology Press，1979： 27，85.
[2] DING W L，CHEN Z，CHEN J. Research on resource and utilization of medicinal plants of genus Trollius [J]. Chin Wild Plant Res (中国野生植物资源，2003，22 (6： 19-21.
[3] WU L Z，XU X D，YANG J S. Research progress on plants of the Trollius genus [J]. Nat Prod Res Dev (天然产物研究与开发，2010，22： 236-239.
[4] SHIMOMURA H，SASHIDA Y，ADACHI T. Phenolic glucosides from Prunus grayana [J]. Phytochemistry，1987，26 (1： 249-251.
[5] SARACOGLU I，VAREL M，HARPUT U S，et al. Acylated flavonoids and phenol glycosides from Veronica thymoides subsp. Pseudocinerea [J]. Phytochemistry，2004，65：2379-2385.
[6] YANG W Z，WANG H，SHANG J，et al. Chemical constituents from Cichorium glandulosum [J]. Chin J Nat Med(中国天然药物， 2009，7 (3： 193-195.
PDF(400 KB)

Accesses

Citation

Detail
段落导航
相关文章

/

〈 〉