肝毒性生物标志物研究进展

耿兴超 沈连忠 李波 王军志

中国药学杂志 ›› 2011, Vol. 46 ›› Issue (10) : 721-724.

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PDF(715 KB)
中国药学杂志 ›› 2011, Vol. 46 ›› Issue (10) : 721-724.
综述

肝毒性生物标志物研究进展

  • 耿兴超,沈连忠,李波*,王军志
作者信息 +
文章历史 +

摘要

目的 综述近年来肝毒性生物标志物的研究现状和最新进展。 方法 通过查阅与肝毒性生物标志物相关的国内外文献报道和美国FDA相关指导原则,对传统的和新发现的肝毒性标志物的研究现状和最新进展进行总结和分析。 结果结论 近年来,肝毒性生物标志物的研究已取得了很大的进步,许多新的肝毒性生物标志物在灵敏度和特异性方面都超过了传统肝毒性生物标志物,但是目前肝毒性生物标志物的研究中仍存在许多问题,还需要开展更多的研究和验证工作。

关键词

肝毒性 / 生物标志物 / 临床研究 / 临床前研究 / 临床检验 / 基因组学

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耿兴超 沈连忠 李波 王军志. 肝毒性生物标志物研究进展[J]. 中国药学杂志, 2011, 46(10): 721-724

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