摘要
目的 进一步研究瘤果槲寄生的化学成分。方法 应用硅胶柱色谱、凝胶柱色谱等各种色谱技术对瘤果槲寄生化学成分进行分离、纯化,并利用理化数据分析和光谱分析方法 鉴定化合物的结构。结果 分离并鉴定出8个三萜及三萜皂苷化合物,分别为羽扇豆醇硬脂酸酯(Ⅰ、羽扇豆醇棕榈酸酯(Ⅱ、β-香树脂醇乙酸酯(Ⅲ、常春藤皂苷元(Ⅳ、丝石竹酸 (Ⅴ、常春藤皂苷元-3-O-α-L-吡喃阿拉伯糖苷(Ⅵ、常春藤皂苷元-3-O-α-L-吡喃阿拉伯糖基(2→1-β-D-吡喃葡萄糖苷(Ⅶ、3-O-α-L-吡喃阿拉伯糖-常春藤皂苷元-28-O-β-D-吡喃葡萄糖基(1→6-β-D-吡喃葡萄糖苷(Ⅷ。结论 化合物Ⅰ~Ⅷ为首次从本植物中分离得到,其中化合物Ⅳ~Ⅷ为首次从槲寄生属植物中分离得到。
Abstract
OBJECTIVE To study the chemical constituents of Viscum ovalifolium DC,further. METHODS Chemical constituents were isolated from the title plant by various chromatographic methods such as silica gel medium pressure column, sephadex LH-20 column chromatography, et al. Their structures were elucidated by physiochemical and spectral analysis. RESULTS Eight triterpenoids and triterpenoid saponins were isolated and identified as lupeol stearate (Ⅰ, lupeol palmitate (Ⅱ, β-amyrin acetate(Ⅲ, hederagenin (Ⅳ, gypsogenic acid (Ⅴ, hederagenin-3-O-α-L-arabinopyranoside (Ⅵ, hederagenin-3-O-α-L-arabinopyranoyl-(2→1-O-β-D-glucopyranoside (Ⅶ, 3-O-α-L-arabinopyranoyl- hederagenin-28-O-β-D-glucopyranosyl-(1→6-β-D-glucopyranoside (Ⅷ. CONCLUSION Compound Ⅰ-Ⅷ were isolated from this plant for the first time, compound Ⅳ-Ⅷ were isolated from Viscum for the first time.
关键词
瘤果槲寄生 /
化学成分 /
结构鉴定
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Key words
Viscum ovalifolium DC /
chemical constituents /
structuents determination
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杨燕军 沙聪威 陈梅果.
瘤果槲寄生化学成分的研究(Ⅱ[J]. 中国药学杂志, 2011, 46(1): 11-13
YNG Yn-jun;SH Cong-wei;CHEN Mei-guo.
Constituents of Viscum ovalifolium DC(Ⅱ[J]. Chinese Pharmaceutical Journal, 2011, 46(1): 11-13
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脚注
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