[1] HARISH K V, PRASHANTH R N T. Chitin/chitosan:modifications and their unlimited application potential- an overview [J]. Trends Food Sci Technol, 2007,18(2):17-131. [2] MAEDA H, WU J, SAWA T, et al. Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review [J]. J Controlled Release, 2006, 5(13): 271-284. [3] MAEDA H .SAMCS and poly-conjugated macromolecular drugs: Advantages in cancer chemotherapy [J]. Adv Drug Deliv Rev, 1991,6(22):181-202. [4] GREISH K, FANG J, INUTSUKA A, et al. Macromolecular therapeutics: advantages and prospects with special emphasis on solid tumor targeting [J]. Clin Pharmacokinet, 2003, 42(16): 1089-1105. [5] KEISUKE K. Controlled functionlization of the polysaccharide chitin [J]. Prog Polym Sci, 2001, 26(7): 1921-1971. [6] YING G Q, YANG H, LI D H, et al. Synthesis and properties of novel hyaluronic acid-like chitosan[J]. Chem Ind Eng Prog(化工进展), 2007,3(26): 405-408. [7] JIANG T D.CHITIN(甲壳素)[M]. Beijing:Chemical Industry Press, 2003: 156. [8] PARK I K, YANG J, JEONG H J, et al. Galactosylated chitosan as a synthetic extracellular matrix for hepatocytes attachment. [J]. Biomaterials, 2003, 24(1): 2331-2337. [9] SONG Y H, HIRAKU O, YOSHIHARU M A, et al. Drug release and antitumor characteristics of N-succinyl-chitosan mitomycin C as an implant[J].J Controlled Release,1996,42(23): 93-100.