目的 研究乌饭树叶中黄酮苷类化学成分。 方法 运用多种色谱技术分离乌饭树叶中黄酮苷类成分，采用波谱技术和理化性质确定化合物的结构。 结果 分离得到 12 个化合物，分别鉴定为：柯伊利素 -7- O-<>β- D- 葡萄糖苷 (1) ，欧槲寄生苷乙 (2) ，柯伊利素 -7- O-(6''- O- 对羟基肉桂酰 )-<>β- D- 葡萄糖苷 (3) ，槲皮素 -3- O-<>β- D- 葡萄糖醛酸甲酯苷 (4) ，异鼠李素 -3- O-<>β- D- 葡萄糖苷 ( 5 ) ，槲皮素 -3- O-α-L- 鼠李糖苷 ( 6 ) ，槲皮素 -3- O- α-L- 阿拉伯糖苷 ( 7 ) ，牡荆素 (8) ，槲皮素 -3- O-<>β- D- 半乳糖苷 (9) ，荭草素 (10) ，异荭草素 (11) ，槲皮素 -3- O-<>β- D- 葡萄糖醛酸苷 (12) 。 结论 化合物 1~4 为首次从越橘属植物中分离得到，化合物 5~12 首次从该植物中分离得到。
Abstract
OBJECTIVE To investigate the flavonoid glycosides from the leaves of Vaccinium bracteatum Thunb. METHODS ■Flavonoid glycosides were isolated using various column chromatographic techniques and their structures were elucidated on the basis of spectral data and chemical evidences. RESULTS Twelve compounds were obtained from V. bracteatum Thunb, and they were identified as chrysoeriol-7-O-β-D-glucopyranoside(1), flavogadorinin(2), chrysoeriol-7-O-(6''-O-p- coumaroyl)-β-D- glucopyranoside (3), quercetin-3-O-β-D-glucuronide methyl ester (4), isorhamnetin-3-O-β-D-glucopyranoside (5), quercetin-3- O-α-L-rhamnoside (6), quercetin-3-O-α-L-arabinopyranoside (7), vitexin (8), quercetin-3-O-β-D-galactopyranoside (9), orientin (10), isoorientin (11), quercetin-3-O-β-D-glucuronide (12). CONCLUSION Compounds 1, 2, 3, 4 were isolated from the Vaccinium for the first time，compounds 5, 6, 7, 8, 9, 10, 12 were isolated from this plant for the first time .
关键词
乌饭树 /
黄酮苷 /
柯伊利素 -7- O-<>β- D- 葡萄糖苷 /
欧槲寄生苷乙
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Key words
Vaccinium bracteatum Thunb /
flavonoid glycoside /
chrysoeriol-7-O-β-D-glucopyranoside /
flavogadorinin
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参考文献
[1] CHEN C M, ZHANG N, WANG M. Ethnobotany of Vaccinium bracteatum Thunb. [J] . <>J <> Plant Res Environ ( 植物资源与环境学报 ), 1998, 7 (1): 45-48.
[2] TU P F, LIU J Y, LI J S. Studies on the liposoluble constituents of Vaccinium bracteatum [J]. <>China J Chin Mater Med ( 中国中药杂志 ), 1 997, 22 (7): 423-424.
[3] SHEN J, LIANG J, PENG S L, et al. Chemical constituents from Saussurea stella [J]. <>Nat Prod Res Dev ( 天然产物研究与开发 ), 2004, 16 (5): 391-394.
[4] DING L, LIU G A, HE L, <>et al. Studies on the flavonoid constituents in herb of Eremosparton songoricum [J]. <>China J Chin Mater Med ( 中国中药杂志 ), 2005, 30 (2): 126-128.
[5] LI W D, ZHANG Y H. Flavonoid glycosides from Galeopsis bifida [J]. <> Acta Bot Boreali-Occidentalia Sin ( 西北植物学报 ), 2003, 23 (4): 637-640.
[6] LI L Q, LI M R, ZHU A J. Studies on the chemical constituents of Taxillus levinei [J]. China J Chin Mater Med ( 中国中药杂志 ), 1996, 21 (1): 34-35.
[7] ZHANG C F, SUN Q S, ZHAO Y Y, <> et al . Studies on flavonoids from leaves of Lindera aggregata (Sims) Kosterm [J]. <> Chin J Med Chem ( 中国药物化学杂志 ), 2001, 11 (5): 274-276.
[8] ZHOU Y J, XU S X, SUN Q S, <>et al. A study on the chemical constituents of Quercus engleriana seem [J]. <> J Shenyang Pharm Univ ( 沈阳药科大学学报 ), 2000, 17 (4): 263-266.
[9] WEN Z L, XU L X. Isolation and elucidation of chemical constituents of Shandanshaoyao decoction ( II )[J]. <>China J Chin Mater Med ( 中国中药杂志 ), 2001, 26 (7): 474-476.
[10] ZHOU X, PENG J Y, FAN G R. Isolation and purification of flabonoid glycisides from Trollius ledebouri using high-speed counter-current chromatography by stepwise increasing the flow-rate of the mobile phase [J]. <>J Chromatogr A, 2005, 1092(1): 216 - 221.
[11] PENG J Y, FAN G R, HONG Z Y. Preparative separation of isovitexin and isoorientin from Patrinia villosa Juss by high-speed counter-current chromatography [J]. <> J Chromatogr A , 2005, 1074(1-2): 111 - 115.
（ 收稿日期 ： 2009-04-05 ）
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