滇藏五味子化学成分研究

徐秀梅;廖志华 ;陈敏

中国药学杂志 ›› 2009, Vol. 44 ›› Issue (23) : 1769-1772.

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中国药学杂志 ›› 2009, Vol. 44 ›› Issue (23) : 1769-1772.
论文

滇藏五味子化学成分研究

  • 徐秀梅 1,2 ,廖志华 1 ,陈敏 3*
作者信息 +

Studies on Chemical Constituents of Schisandra neglecta A.C. Smith

  • XU Xiu-mei1,2 , LIAO Zhi-hua1 , CHEN Min3*
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摘要

目的 研究滇藏五味子( Schisandra neglecta A.C. Smith )的化学成分。 方法 用硅胶柱色谱、制备 HPLC 和制备 TLC 进行分离,通过理化性质和光谱数据进行结构鉴定。 结果 从滇藏五味子的茎藤中分离得到 9 个木脂素和 1 个三萜酸,分别是乙酰戈米辛 R (Ⅰ)、五味子酚乙(Ⅱ)、( - ) - 戈米辛 L1 (Ⅲ)、苯甲酰戈米辛 P (Ⅳ)、顺芷酰戈米辛 P (Ⅴ)、戈米辛 R (Ⅵ)、南五味子素(Ⅶ)、南五味子酸(Ⅷ)、表戈米辛 O (Ⅸ)、戈米辛 O (Ⅹ)。 结论 所有化合物均首次从该植物中分离得到。

Abstract

OBJECTIVE To study the chemical constituents of Schisandra neglecta. METHODS The chemical constituents were isolated by silica gel , prep-HPLC and prep-TLC methods. And their structures were elucidated by physical-chemical and spectroscopic methods. RESULTS Nine dibenzocyclooctadiene lignans, acetylgomisin R (Ⅰ), schisanhenol B (Ⅱ), (-)-gomisin L1 (Ⅲ), benzoylgomisin P (Ⅳ), tigloylgomisin P (Ⅴ), gomisin R (Ⅵ), kadsurin (Ⅶ), epigomisin O (Ⅸ), gomisin O (Ⅹ)and one kadsuric acid(Ⅷ) were isolated from the stem of S. neglecta. CONCLUSION All compounds were isolated from the plant for the first time.

关键词

滇藏五味子 / 化学成分 / 木脂素 / 三萜酸

Key words

Schisandra neglecta / chemical constituents / lignan / triterpene acid

引用本文

导出引用
徐秀梅;廖志华 ;陈敏 . 滇藏五味子化学成分研究[J]. 中国药学杂志, 2009, 44(23): 1769-1772
XU Xiu-mei;LIO Zhi-hu;CHEN Min . Studies on Chemical Constituents of Schisandra neglecta A.C. Smith[J]. Chinese Pharmaceutical Journal, 2009, 44(23): 1769-1772

参考文献


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( 收稿日期 : 2009-04-07 )

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