受体介导的脑靶向药物递送系统研究进展

杨媛;娄琨;梅兴国 ;吕万良

中国药学杂志 ›› 2009, Vol. 44 ›› Issue (23) : 1761-1764.

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中国药学杂志 ›› 2009, Vol. 44 ›› Issue (23) : 1761-1764.
论文

受体介导的脑靶向药物递送系统研究进展

  • 杨媛 1,2 ,娄琨 2 ,梅兴国 2 * ,吕万良 3
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文章历史 +

摘要

目的 介绍受体介导的脑靶向药物递送系统的最新研究进展。 方法 对有代表性的受体介导的脑靶向药物递送系统研究情况进行分析和总结。 结果 受体介导的脑部药物递送特别是转铁蛋白受体和胰岛素受体介导的脑靶向作用备受关注,相关配体或抗体可与药物、生物活性物质、脂质体、纳米粒等相连,提高药物或载体透过血脑屏障的能力。 结论 受体介导机制在脑部药物递送研究领域具有广阔的应用前景。

关键词

血脑屏障 / 受体介导 / 脑靶向 / 药物递送系统

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导出引用
杨媛;娄琨;梅兴国 ;吕万良 . 受体介导的脑靶向药物递送系统研究进展[J]. 中国药学杂志, 2009, 44(23): 1761-1764

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( 收稿日期 : 2009-04-10 )

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