荨麻根中化学成分的研究

冀保全;冯宝民 ;史丽颖;唐玲;王永奇

中国药学杂志 ›› 2009, Vol. 44 ›› Issue (18) : 1372-1374.

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中国药学杂志 ›› 2009, Vol. 44 ›› Issue (18) : 1372-1374.
论文

荨麻根中化学成分的研究

  • 冀保全,冯宝民 * ,史丽颖,唐玲,王永奇
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摘要

目的 对荨麻根的化学成分进行研究。 方法 采用硅胶柱色谱、凝胶柱色谱、制备薄层色谱等各种色谱技术对荨麻根的化学成分进行分离,应用理化数据分析和波谱分析方法鉴定化合物的结构。 结果 从荨麻根中分离得到 10 个化合物,分别为 α - 香树脂醇 ( Ⅰ ) 、 β - 香树脂醇 (Ⅱ)、齐墩果酸 (Ⅲ)、 双( 5- 甲酰基糠基)醚(Ⅳ)、 5- 羟甲基糠醛(Ⅴ)、 4- 羟基苯甲酸 (Ⅵ)、东莨菪素(Ⅶ)、东莨菪素苷(Ⅷ)、胡萝卜苷(Ⅸ)和 β - 谷甾醇(Ⅹ)。 结论 化合物Ⅰ ~ Ⅶ均为首次从荨麻中分离得到。

Abstract

OBJECTIVE To study the chemical constituents of the roots of Urtica fissa E. Pritz. METHODS Chemical constituents were isolated by various chromatographic methods such as silica gel column, sephadex LH-20 column chromatography and PTLC. Their structures were determined by physiochemical and spectral analysis. RESULTS Ten compounds were isolated and identified as α-amyrin (Ⅰ), β-amyrin (Ⅱ), oleanolic acid(Ⅲ), bis(5-formylfurfuryl)ether(Ⅳ), 5-hydroxylmethylfuraldehyde(Ⅴ), 4-hydroxybenzoic acid(Ⅵ), scopoletin(Ⅶ), scopolin(Ⅷ), daucosterol(Ⅸ), β-sitosterol(Ⅹ). CONCLUSION ■Compound Ⅰ-Ⅶ were isolated from Urtica fissa E. Pritz. for the first time.

关键词

荨麻 / 化学成分 / 结构鉴定

Key words

Uritca fissa E. Pritz. / chemical constituents / structural determination

引用本文

导出引用
冀保全;冯宝民 ;史丽颖;唐玲;王永奇 . 荨麻根中化学成分的研究[J]. 中国药学杂志, 2009, 44(18): 1372-1374

参考文献


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( 收稿日期 : 2009-01-12 )


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