摘要
目的研究豆科植物植藤子[Entada phaseoloides(L.)Merr.]种仁的化学成分。方法采用硅胶,Sephadex LH-20等分离纯化,通过理化常数测定和现代波谱学技术(MS、1H-NMR、13C-NMR)进行结构鉴定。结果分离得到8个化合物,分别为2,5-二羟基苯乙酸乙酯(1),2,5-二羟基苯乙酸甲酯(2),5-羟基-苯并呋喃-2-酮(3),榼藤酰胺A(4),硬脂酸甲酯(5),β-谷甾醇(6),胡萝卜苷(7),豆甾醇(8)。结论化合物1,3,5,7,8为首次从该属植物中分离得到,6为首次从该植物中分离得到。
Abstract
OBJECTIVE To study the chemical constituents of Entada phaseoloides.METHODS The constituents were isolated and purified by the silica gel and Sephadex LH-20 chromatography,and their structures were elucidated based on their physieochemical properties and spectral data.RESULTS Eight compounds were isolated and identified as ethyl 2,5-dihydroxy phenyl acetate(1),methyl 2,5-dihydroxy phenyl acetate(2),5-hydroxybenzofuran-2(3H)-one(3),entadamide A(4),methyl stearate(5),β-sitosterol(6),β-daucosterol(7)and stigmasterol(8).CONCLUSION Compound 1,3,5,7 and 8 were isolated from Entada genus for the first time and compound 6 was isolated from Entada phaseoloides for the first time.
关键词
豆科 /
榼藤子 /
化学成分 /
2 /
5-二羟基苯乙酸
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Key words
Leguminosae /
Entada phaseoloides /
chemical constituents /
2 /
5-dihydroxyphenylacetic acid
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张勇;张宏武;邹忠梅.
榼藤子种仁化学成分研究[J]. 中国药学杂志, 2008, 43(14): 1063-1065
ZHNG Yong;ZHNG Hong-wu;ZOU Zhong-Mei.
Studies on Chemical Constituents in Seeds of Entada phaseoloide[J]. Chinese Pharmaceutical Journal, 2008, 43(14): 1063-1065
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参考文献
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脚注
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基金
中央公益性科研院所基本科研业务专项(YZ-08-02)
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