过山蕨中黄酮类成分的研究

李宁;李铣;冯志国;杨世林

中国药学杂志 ›› 2007, Vol. 42 ›› Issue (14) : 1049-1051.

中国药学杂志
中国药学杂志 ›› 2007, Vol. 42 ›› Issue (14) : 1049-1051.
论著

过山蕨中黄酮类成分的研究

  • 李宁;李铣;冯志国;杨世林
作者信息 +

Studies on Flavonoidal Constituents from Camptosorus sibiricus Rupr

  • LI Ning1，LI Xian1*，FENG Zhi-guo2，YANG Shi-lin3
Author information +
文章历史 +

摘要

目的研究过山蕨(Camptosorus sibiricus Rupr.)中黄酮类化学成分。方法采用反复硅胶柱色谱法、Sephadex LH-20柱色谱法、高效液相色谱法等进行分离纯化,并通过理化常数测定和光谱分析鉴定了其化学结构。结果从过山蕨70%乙醇提取物中分离得到6个黄酮类化合物,并鉴定其结构为:山柰酚(1);山柰酚-7-O-α-L-鼠李糖苷(2);山柰酚-3-O-β-D-吡喃葡萄糖基(1→2)-β-D-吡喃葡萄糖苷(3);山柰酚-3-O-β-D-吡喃葡萄糖基(1→2)-β-D-吡喃葡萄糖基-7-O-β-D-吡喃葡萄糖苷(4);山柰酚-3-O-β-D-吡喃葡萄糖基-7-O-β-D-吡喃葡萄糖基(1→2)-β-D-吡喃葡萄糖苷(5);山柰酚-3-O-β-D-吡喃葡萄糖基(1→4)-α-L-鼠李糖基-7-O-α-L-鼠李糖苷(6)。结论化合物2,3,4,5,6均为首次从该属植物中分离得到。

Abstract

OBJECTIVE To study the flavonoidal constituents from the 70% ethanol extract of the whole herbal of Camptosorus sibiricus Rupr..METHODS The compounds were isolated by chromatography on silica gel column,Sephadex LH-20 column,preparative HPLC column,and identified on the basis of physico- chemical constants and spectral analysis. RESULTS Six compounds were isolated as kaempferol (1),kaempferol-7-O-α-L-rhamnoside (2),kaempferol 3-O-β-D-glucopyranosyl (1→2) -β-D- glucopyranoside (3),kaempferol- 3-O-β-D- glucopyranosyl (1→2) -β-D-glucopyranosyl -7- O-β-D- glucopyranoside (4),kaempferol-3-O-β-D- glucopyranosyl-7-O-β-D- glucopyranosyl-(1→2)-β-D-glucopyranoside (5),kaempferol 3-O-β-D-glucopyranosyl (1→4) -α-L- rhamnosyl -7-O-α-L-rhamnoside (6) ,respectively.CONCLUSION Compounds 2,3,4,5,6 are obtained from this genus for the first time.

关键词

过山蕨 / 黄酮类成分

Key words

Camptosorus sibiricus Rupr / flavonoids

引用本文

EndNote

Ris (Procite)

Bibtex

导出引用
李宁;李铣;冯志国;杨世林. 过山蕨中黄酮类成分的研究[J]. 中国药学杂志, 2007, 42(14): 1049-1051
LI Ning;LI Xin;FENG Zhi-guo;YNG Shi-lin. Studies on Flavonoidal Constituents from Camptosorus sibiricus Rupr [J]. Chinese Pharmaceutical Journal, 2007, 42(14): 1049-1051

参考文献

[1] YAN Z K. Colorized Picture Records of Chinese Changbai Mountain Materia Medica (中国长白山药用植物彩色图志)[M] . Beijing：People’s Medical Publishing House，1997：96. [2] 41K of Shenyang College of Pharmacy. Dilatation of blood vessels and toxities of Camptosorus sibiricus Rupr. [J] .J Shenyang Coll Pharm（沈阳药学院学报），1977，7 (34)：34-37. [3] XU S X，WANG S X，WANG N L，et al. Studies on the chemical constituents from Camptosorus sibiricus Rupr.(Ⅰ) [J] .Chin Tradit Herb Drugs(中草药)，1983，14 (7)：1-3. [4] XU S X，ZHOU R H，DONG S H. Studies on the chemical constituents from Camptosorus sibiricus Rupr.(Ⅱ) [J] .Chin Tradit Herb Drugs(中草药)，1989，20 (8)：4. [5] XU S X，ZHOU R H，DONG S H. Studies on a new flavonoid from Camptosorus sibiricus Rupr.[J] .J Shenyang Coll Pharm（沈阳药学院学报），1989，6（1）：66. [6] ZHANG B F，WANG S J，PAN W J. Studies on Camptosorus sibiricus Rupr. Used for cardiovascular diseases [J] .Chin Tradit Herb Drugs(中草药)，1979，11(29)：29-35. [8] YU R M，LI X，ZHU T R，et al. Isolation and identification of flavonoids from Oxytropis glabra DC.[J] .J Chin Tradit Med(中国中药杂志)，1989，14 (8)：34-36. [9] AGRAWAI P K.Carbon 13-NMR of Flavonoids[M] .Amsterdan：Elsevier Press，1989：340-341. [10] BUDZIANOWSKI J. Kaempferol glycosides from Host ventricosa[J] . Phytochemistry，1990，29 (11)：3643-3647. [11] VALLEJI F，TOMAS-BARBERAN F A，FERRERES F. Characterisation of flavonols in broccoli (Brassica oleracea L. var. italica) by liquid chromatography-UV diode-array detection-electrospray ionization mass spectrometry[J] .J Chromatogr A，2004，1054：181-193. [12] GUO Y Q. Studies on the chemical constituents and pharmacological activities of fruits of Celastrus orbiculatus Thunb [D] . Shenyang：Shenyang Pharmaceutical University，2003.

Accesses

Citation

Detail
段落导航
相关文章

/

〈 〉