OBJECTIVE To investigate the chemical constituents of Hypericum japonicum.METHODS The compounds were separated by chromatography and their chemical structures were elucidated by means of MS,1H-NMR and 13C-NMR spectral methods,respectively.RESULTS Twelve compounds were isolated from the plant,they were identified as isojacareubin(Ⅰ),quercetin(Ⅱ),kaempferol(Ⅲ),quercetin-7-O-α-L-rhamnoside(Ⅳ),quercitrin(quercetin-3-O-α-L-rhamnoside,Ⅴ),isoquercitrin(quercetin-3-O-β-D-glucoside,Ⅵ),miguelianin(quercetin-3-O-β-D-glucuronide,Ⅶ),bijaponicaxanthone(Ⅷ),3,8″-biapigenin(Ⅸ),betulinic acid(Ⅹ),stigmasterol(Ⅺ) and stigmasterol-3-O-β-D-glucopyranoiside(Ⅻ).CONCLUSION Compound Ⅶ,Ⅸ and Ⅻ are isolated from this plant for the first time.
ZHNG Lin;JIN Yun-yun;TIN Jing-kui.
Studies on Chemical Constituents of Hypericum japonicum[J]. Chinese Pharmaceutical Journal, 2007, 42(05): 341-344
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