金钱草中黄酮类化合物的分离与结构鉴定

杨念云;段金廒;李萍;钱士辉

中国药学杂志 ›› 2006, Vol. 41 ›› Issue (21) : 1621-1623.

中国药学杂志 ›› 2006, Vol. 41 ›› Issue (21) : 1621-1623.
论著

金钱草中黄酮类化合物的分离与结构鉴定

  • 杨念云,;段金廒;李萍;钱士辉
作者信息 +

Studies on Flavonoids of Lysimachia christinae Hance

  • YANG Nian-yun1,2 ,DUAN Jin-ao2,LI Ping1*,QIAN Shi-hui2
Author information +
文章历史 +

摘要

目的对金钱草全草进行了较系统的化学成分研究。方法应用多种色谱法分离金钱草中的化学成分,采用多种光谱分析法鉴定它们的结构。结果从金钱草全草中分离得到12个黄酮类化合物,即异鼠李素(1)、山柰酚(2)、槲皮素(3)、黄芪苷(4)、三叶豆苷(5)、金丝桃苷(6)、蒙花苷(7)、橙皮苷(8)、异鼠李素-3-O-β-D-刺槐双糖苷(9)、山柰酚-3-O-β-D-刺槐双糖苷(10)、芦丁(11)、新西兰牡荆苷-2(12)。结论化合物1,6,9,10,11均为首次从该种植物中分离得到;化合物7、8、12均为首次从该属植物中分离得到。

Abstract

OBJECTIVE To study the chemical constituents of Lysimachia christinae.METHODS Manifold chromatography methods were used to separated the chemical constituents,and the chemical structures were determined by spectral analysis.RESULTS Twelve compounds were isolated from Lysimachia christinae and identified as: isorhamnetin(1),kaempferol(2),quercetin(3),astragalin(4),trifolin(5),hyperin(6),linarin(7),hesperidin(8),isorhamnetin-robinobioside(9),kaempferol-robinobioside(10),rutin(11),vicenin-2 (12). CONCLUSION Compound 1,6,9,10 and 11 are isolated from this plant for the first time,compound 7,8 and 12 are isolated from this genus for the first time.

关键词

金钱草 / 黄酮类化合物 / 结构鉴定

Key words

Lysimachia christinae / flavonoid / structure identification

引用本文

导出引用
杨念云;段金廒;李萍;钱士辉. 金钱草中黄酮类化合物的分离与结构鉴定[J]. 中国药学杂志, 2006, 41(21): 1621-1623
YNG Nin-yun;DUN Jin-o;LI Ping;QIN Shi-hui. Studies on Flavonoids of Lysimachia christinae Hance [J]. Chinese Pharmaceutical Journal, 2006, 41(21): 1621-1623

参考文献

[1] Editorial Committee(over 300 members)of the Administration Bureau of Traditional Chinese Medicine.Chinese Materia Medica(中华本草)[M] . Vol. 6,Shanghai: Shanghai Science & Technology Press,1999: 5357-5362. [2] YU D Q,YANG J S.Handbook of Analytical Chemistry(分析化学手册)[M] .Vol. 7,Beijing: Chemical Industry Press,1999: 820,837,838. [3] ?LU Y H. Total synthesis of luteolin and kaempferol[J] .Acta Pharm Sin(药学学报),1980,(8):477-479. [4] MUNEHISA A,MASAKO H,MIYA S. Flavonoids from Salvia tomentosa[J] .Shoyakugaku Zasshi,1984,38(3): 215-218. [5] LI J S,ZHAO Y Y,LI X L. Seperation and identification of flavonoids from Buddleja officinalis[J] .Acta Pharm Sin(药学学报),1996,31(11): 849-854. [6] QI Y P,GUO S M,XIA Z L,et al.Study on the chemical constituents of Bombax malabaricum(Ⅱ)[J] .Chin J Chin Mater Med(中国中药杂志),1996,21(4): 234-235. [7] KEN Y,MICHIO T. Quercetin 3-rhamnosyl(1→2)Galactoside from Lysimachia vulgaris var.davurica[J] .Phytochemistry,1988,27(9): 3017-3019. [8] WANG Y Q,LV L,JIANG Y,et al. Study on the chemical constituents of Lespedeza tomentosa[J] .Chin Tradit Herb Drugs(中草药),1992,23(7): 341-343.

基金

江苏省科技攻关项目(BE2003610)

39

Accesses

0

Citation

Detail

段落导航
相关文章

/