摘要
目的对海南含羞草化学成分进行研究。方法采用DiaionHP-20,ToyopearlHW-40,SephadexLH-20,RP18、硅胶等柱色谱技术进行分离纯化,用ESI-MS,IR,1H-NMR,13C-NMR,1H-1H COSY,HSQC,HMBC技术及理化性质鉴定化合物的结构。结果分离鉴定了5个化合物:5,7,3′,4′-四羟基-6-C-β-D-葡萄糖黄酮碳苷(Ⅰ),5,7,3′,4′-四羟基-8-C-β-D-葡萄糖黄酮碳苷(Ⅱ),丁二酸(Ⅲ),β-谷甾醇(Ⅳ),豆甾醇(Ⅴ)。结论这些化合物均系首次从该植物中分离得到。
Abstract
OBJECTIVE To study chemical constituents of Mimosa pudica in Hainan province. METHODS The compounds were separated by Diaion HP-20, Sephadex LH-20, Toyopearl HW-40, RP-18, and silica gel column chromatography,et al. The structures were elucidated by means of ESI-MS, IR,1H-NMR,13C-NMR,1H-1H COSY, HSQC and HMBC spectral method respectively. RESULTS Five compounds were isolated and identified from the plants. They were established as 5,7,3′,4′-tetrahydroxyl-6-C-β-D-glucopyranosyl flavone(Ⅰ), 5,7,3′,4′-tetrahydroxyl-8-C-β-D-glucopyranosyl flavone(Ⅱ), succinic acid(Ⅲ), β-sitosterol(Ⅳ)and stigmasterol(Ⅴ). CONCLUSION These compounds are isolated from the plant for the first time.
关键词
含羞草 /
化学成分
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Key words
Mimosa pudica /
chemical constituents
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袁珂;吕洁丽;贾安.
含羞草化学成分的研究[J]. 中国药学杂志, 2006, 41(17): 1293-1294
YUN Ke;Lü Jie-li;JI n.
Studies on Chemical Constituents of Mimosa pudica[J]. Chinese Pharmaceutical Journal, 2006, 41(17): 1293-1294
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参考文献
[1] JIANGSU NEW MEDICAL COLLEGE. Big Thesaurus of Traditional Chinese Medicine(中药大词典)[M] . Shanghai： Science and Technique Publishing Company of Shanghai，1986：1147-1148.
[2] State Administration of Traditional Chinese Medicine. China Herbal(中华本草)[M] . Shanghai： Science and Technique Publishing Company of Shanghai，1999：573-574.
[3] Editorial Board of Compendium of Chinese Traditional Herbal Drugs. Compendium of Chinese Tradional Herbal Drugs(全国中草药汇编) [M] . Vol 2. Beijing：People's Medical Publishing House，1975：464.
[4] WANG S S，XU Q，XIAO H B，et al. Glycoside constituents from Swertia franchetiana[J] .Chin Tradit Herb Drugs(中草药)，2004，35(8)：847-849.
[5] LI H Y，SUN J Y，DAI S W. Studies on chemical constituents from Phyllostachys pubescens[J] .J Chin Med Mater(中药材)，2003，26(8)：562-563.
[6] SONG D M，SUN Q S.Chemical studies on the constituents of Trollius altaicus C. A. Mey[J] .Chin J Medic Chem(中国药物化学杂志)，2004，14(4)：233-235.
[7] FENG S L，HE L，WANG M，et al. Studies on chemical constituents of Lilium davidii Duch var unicolor Cotton [J] .China J Chin Mater Med(中国中药杂志)，1994，19(10)：611-612.
[8] RUBINSTEIN I，GOAD J L，CLAGUE A D H，et al. The 220 MHz NMR spectra of phytosterols[J] .Phytochemistry，1976，15(1)：195.
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脚注
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