摘要
目的对光茎大黄根的化学成分进行研究。方法采用硅胶柱色谱、重结晶等方法进行分离,利用现代波谱技术(MS,1H-NMR,13C-NMR)及理化性质进行结构鉴定。结果从该植物根中分离并鉴定了5个化合物,分别是:邻苯二甲酸二丁酯(Ⅰ),大黄素-8-O-β-D-葡萄糖苷(Ⅱ),芦荟大黄素-3-(羟甲基)-O-β-D-葡萄糖苷(Ⅲ),β-谷甾醇-3-O-β-D-(6′-十七碳酰基)葡萄糖苷(Ⅳ),山柰酚(Ⅴ)。结论该5个化合物均为首次从该植物中分离得到。
Abstract
OBJECTIVE To study the chemical constituents in the root of Rheum glabricaule.METHODS Compounds were isolated by various column chromatographies with silica gel.Their structures were elucidated by spectral analysis(MS,1H-NMR,13C-NMR) and chemical evidence.RESULTS Five compounds were isolated from this plant,and identified as dibutyl phthalate(Ⅰ),emodin-8-O-β-D-glucopyranoside(Ⅱ),aloe-emodin-3-(hydroxymethyl)-O-β-D-glucopyranoside(Ⅲ),β-sitosterol-3-O-β-D-(6′-O-acyl)-glucopyranoside(Ⅳ) and kaempferol(Ⅴ),respectively.CONCLUSION All above compounds are obtained from this plant for the first time.
关键词
蓼科 /
光茎大黄 /
化学成分
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Key words
Polygonaceae /
Rheum glabricaule Sam. /
chemical constituents
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魏玉辉;武新安;张承忠;李冲;宋龙.
光茎大黄化学成分研究(Ⅱ)[J]. 中国药学杂志, 2006, 41(04): 253-254
WEI Yu-hui;WU Xin-n;ZHNG Cheng-zhong;LI Chong;SONG Long.
Studies on Chemical Constituents of Rheum glabricaule Sam.(Ⅱ) [J]. Chinese Pharmaceutical Journal, 2006, 41(04): 253-254
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参考文献
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脚注
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